Drug safety assessment in clinical trials: methodological challenges and opportunities
<p>Abstract</p> <p>Randomized controlled trials are the principal means of establishing the efficacy of drugs. However pre-marketing trials are limited in size and duration and exclude high-risk populations. They have limited statistical power to detect rare but potentially serious...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-08-01
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| Series: | Trials |
| Online Access: | http://www.trialsjournal.com/content/13/1/138 |