Mechanisms of Transforming DNA Uptake to the Periplasm of Bacillus subtilis
Transformation is a widely distributed mechanism of bacterial horizontal gene transfer that plays a role in the spread of antibiotic resistance and virulence genes and more generally in evolution. Although transformation was discovered nearly a century ago and most, if not all the proteins required...
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| Format: | Article |
| Language: | English |
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American Society for Microbiology
2021-06-01
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| Series: | mBio |
| Online Access: | https://journals.asm.org/doi/10.1128/mBio.01061-21 |
| _version_ | 1818889393762467840 |
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| author | Jeanette Hahn Micaela DeSantis David Dubnau |
| author_facet | Jeanette Hahn Micaela DeSantis David Dubnau |
| author_sort | Jeanette Hahn |
| collection | DOAJ |
| description | Transformation is a widely distributed mechanism of bacterial horizontal gene transfer that plays a role in the spread of antibiotic resistance and virulence genes and more generally in evolution. Although transformation was discovered nearly a century ago and most, if not all the proteins required have been identified in several bacterial species, much remains poorly understood about the molecular mechanism of DNA uptake. |
| first_indexed | 2024-12-19T17:08:19Z |
| format | Article |
| id | doaj.art-b68f0c3d4e9541168a946382ee9951b3 |
| institution | Directory Open Access Journal |
| issn | 2150-7511 |
| language | English |
| last_indexed | 2024-12-19T17:08:19Z |
| publishDate | 2021-06-01 |
| publisher | American Society for Microbiology |
| record_format | Article |
| series | mBio |
| spelling | doaj.art-b68f0c3d4e9541168a946382ee9951b32022-12-21T20:13:06ZengAmerican Society for MicrobiologymBio2150-75112021-06-0112310.1128/mBio.01061-21Mechanisms of Transforming DNA Uptake to the Periplasm of Bacillus subtilisJeanette Hahn0Micaela DeSantis1David Dubnau2https://orcid.org/0000-0001-9713-6120Public Health Research Institute, Rutgers University, Newark, New Jersey, USAPublic Health Research Institute, Rutgers University, Newark, New Jersey, USAPublic Health Research Institute, Rutgers University, Newark, New Jersey, USATransformation is a widely distributed mechanism of bacterial horizontal gene transfer that plays a role in the spread of antibiotic resistance and virulence genes and more generally in evolution. Although transformation was discovered nearly a century ago and most, if not all the proteins required have been identified in several bacterial species, much remains poorly understood about the molecular mechanism of DNA uptake.https://journals.asm.org/doi/10.1128/mBio.01061-21 |
| spellingShingle | Jeanette Hahn Micaela DeSantis David Dubnau Mechanisms of Transforming DNA Uptake to the Periplasm of Bacillus subtilis mBio |
| title | Mechanisms of Transforming DNA Uptake to the Periplasm of Bacillus subtilis |
| title_full | Mechanisms of Transforming DNA Uptake to the Periplasm of Bacillus subtilis |
| title_fullStr | Mechanisms of Transforming DNA Uptake to the Periplasm of Bacillus subtilis |
| title_full_unstemmed | Mechanisms of Transforming DNA Uptake to the Periplasm of Bacillus subtilis |
| title_short | Mechanisms of Transforming DNA Uptake to the Periplasm of Bacillus subtilis |
| title_sort | mechanisms of transforming dna uptake to the periplasm of bacillus subtilis |
| url | https://journals.asm.org/doi/10.1128/mBio.01061-21 |
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