Extending resection and preserving function: modern concepts of glioma surgery
Recent studies have demonstrated that the improved prognosis derived from resection of gliomas largely depends on the extent and quality of the resection, making maximum but safe resection the ultimate goal. Simultaneously, technical innovations and refined neurosurgical methods have rapidly impro...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SMW supporting association (Trägerverein Swiss Medical Weekly SMW)
2015-01-01
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| Series: | Swiss Medical Weekly |
| Subjects: | |
| Online Access: | https://www.smw.ch/index.php/smw/article/view/1977 |
| _version_ | 1811194293068496896 |
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| author | Philippe Schucht Juergen Beck Kathleen Seidel Andreas Raabe |
| author_facet | Philippe Schucht Juergen Beck Kathleen Seidel Andreas Raabe |
| author_sort | Philippe Schucht |
| collection | DOAJ |
| description |
Recent studies have demonstrated that the improved prognosis derived from resection of gliomas largely depends on the extent and quality of the resection, making maximum but safe resection the ultimate goal. Simultaneously, technical innovations and refined neurosurgical methods have rapidly improved efficacy and safety. Because gliomas derive from intrinsic brain cells, they often cannot be visually distinguished from the surrounding brain tissue during surgery. In order to appreciate the full extent of their solid compartment, various technologies have recently been introduced. However, radical resection of infiltrative glioma puts neurological function at risk, with potential detrimental consequences for patients’ survival and quality of life. The allocation of various neurological functions within the brain varies in each patient and may undergo additional changes in the presence of a tumour (brain plasticity), making intra-operative localisation of eloquent areas mandatory for preservation of essential brain functions. Combining methods that visually distinguish tumour tissue and detect tissues responsible for critical functions now enables resection of tumours in brain regions that were previously considered off-limits, and benefits patients by enabling a more radical resection, while simultaneously lowering the risk of neurological deficits. Here we review recent and expected developments in microsurgery for glioma and their respective benefits.
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| first_indexed | 2024-04-12T00:24:40Z |
| format | Article |
| id | doaj.art-b6960f9785e54f43a1ad25e171c245de |
| institution | Directory Open Access Journal |
| issn | 1424-3997 |
| language | English |
| last_indexed | 2024-04-12T00:24:40Z |
| publishDate | 2015-01-01 |
| publisher | SMW supporting association (Trägerverein Swiss Medical Weekly SMW) |
| record_format | Article |
| series | Swiss Medical Weekly |
| spelling | doaj.art-b6960f9785e54f43a1ad25e171c245de2022-12-22T03:55:35ZengSMW supporting association (Trägerverein Swiss Medical Weekly SMW)Swiss Medical Weekly1424-39972015-01-01145050610.4414/smw.2015.14082Extending resection and preserving function: modern concepts of glioma surgeryPhilippe SchuchtJuergen BeckKathleen SeidelAndreas Raabe Recent studies have demonstrated that the improved prognosis derived from resection of gliomas largely depends on the extent and quality of the resection, making maximum but safe resection the ultimate goal. Simultaneously, technical innovations and refined neurosurgical methods have rapidly improved efficacy and safety. Because gliomas derive from intrinsic brain cells, they often cannot be visually distinguished from the surrounding brain tissue during surgery. In order to appreciate the full extent of their solid compartment, various technologies have recently been introduced. However, radical resection of infiltrative glioma puts neurological function at risk, with potential detrimental consequences for patients’ survival and quality of life. The allocation of various neurological functions within the brain varies in each patient and may undergo additional changes in the presence of a tumour (brain plasticity), making intra-operative localisation of eloquent areas mandatory for preservation of essential brain functions. Combining methods that visually distinguish tumour tissue and detect tissues responsible for critical functions now enables resection of tumours in brain regions that were previously considered off-limits, and benefits patients by enabling a more radical resection, while simultaneously lowering the risk of neurological deficits. Here we review recent and expected developments in microsurgery for glioma and their respective benefits. https://www.smw.ch/index.php/smw/article/view/1977gliomaglioblastomaneurosurgeryCNS tumor5-ALA |
| spellingShingle | Philippe Schucht Juergen Beck Kathleen Seidel Andreas Raabe Extending resection and preserving function: modern concepts of glioma surgery Swiss Medical Weekly glioma glioblastoma neurosurgery CNS tumor 5-ALA |
| title | Extending resection and preserving function: modern concepts of glioma surgery |
| title_full | Extending resection and preserving function: modern concepts of glioma surgery |
| title_fullStr | Extending resection and preserving function: modern concepts of glioma surgery |
| title_full_unstemmed | Extending resection and preserving function: modern concepts of glioma surgery |
| title_short | Extending resection and preserving function: modern concepts of glioma surgery |
| title_sort | extending resection and preserving function modern concepts of glioma surgery |
| topic | glioma glioblastoma neurosurgery CNS tumor 5-ALA |
| url | https://www.smw.ch/index.php/smw/article/view/1977 |
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