The Nef activity on HIV-1 infectivity
The replication and pathogenicity of lentiviruses is crucially modulated by auxiliary proteins which are expressed in addition to the canonical retroviral ORFs gag, pol and env. Strategies to inhibit the activity of such proteins are often sought and proposed as possible additions to increase effica...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-05-01
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Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00232/full |