The Nef activity on HIV-1 infectivity

The replication and pathogenicity of lentiviruses is crucially modulated by auxiliary proteins which are expressed in addition to the canonical retroviral ORFs gag, pol and env. Strategies to inhibit the activity of such proteins are often sought and proposed as possible additions to increase effica...

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Bibliographic Details
Main Authors: Stéphane eBasmaciogullari, Massimo ePizzato
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00232/full