Utilization of Aminoguanidine Prevents Cytotoxic Effects of Semen

Utilization of Aminoguanidine Prevents Cytotoxic Effects of Semen

Studies of human semen in cell or tissue culture are hampered by the high cytotoxic activity of this body fluid. The components responsible for the cell damaging activity of semen are amine oxidases, which convert abundant polyamines, such as spermine or spermidine in seminal plasma into toxic inter...

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Bibliographic Details
Main Authors: Mirja Harms, Pascal von Maltitz, Rüdiger Groß, Benjamin Mayer, Miriam Deniz, Janis Müller, Jan Münch
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
seminal fluid
cytotoxicity
polyamines
spermine
Online Access:https://www.mdpi.com/1422-0067/23/15/8563

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