Probing the stress and depression circuits with a disease gene

Selectively deleting a gene that has been linked to depression from specific neurons in mice sheds new light on a neural circuit that controls stress-induced depressive behaviors.

Bibliographic Details
Main Authors: Chang Sin Park, X William Yang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/10829
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author Chang Sin Park
X William Yang
author_facet Chang Sin Park
X William Yang
author_sort Chang Sin Park
collection DOAJ
description Selectively deleting a gene that has been linked to depression from specific neurons in mice sheds new light on a neural circuit that controls stress-induced depressive behaviors.
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spelling doaj.art-b69d06959f02403e9f3c77ebd4f8f92b2022-12-22T02:05:18ZengeLife Sciences Publications LtdeLife2050-084X2015-09-01410.7554/eLife.10829Probing the stress and depression circuits with a disease geneChang Sin Park0X William Yang1Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior and the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United StatesCenter for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior and the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United StatesSelectively deleting a gene that has been linked to depression from specific neurons in mice sheds new light on a neural circuit that controls stress-induced depressive behaviors.https://elifesciences.org/articles/10829depressionstressanxietymedial prefrontal cortexwolfram syndromeneuropsychiatric disorder
spellingShingle Chang Sin Park
X William Yang
Probing the stress and depression circuits with a disease gene
eLife
depression
stress
anxiety
medial prefrontal cortex
wolfram syndrome
neuropsychiatric disorder
title Probing the stress and depression circuits with a disease gene
title_full Probing the stress and depression circuits with a disease gene
title_fullStr Probing the stress and depression circuits with a disease gene
title_full_unstemmed Probing the stress and depression circuits with a disease gene
title_short Probing the stress and depression circuits with a disease gene
title_sort probing the stress and depression circuits with a disease gene
topic depression
stress
anxiety
medial prefrontal cortex
wolfram syndrome
neuropsychiatric disorder
url https://elifesciences.org/articles/10829
work_keys_str_mv AT changsinpark probingthestressanddepressioncircuitswithadiseasegene
AT xwilliamyang probingthestressanddepressioncircuitswithadiseasegene