Post-acute COVID and long-COVID among adults and older adults in the State of Paraná, Brazil: protocol for an ambispective cohort study
Introduction Since 2020, the world has been going through a viral pandemic with a high morbidity and mortality rate along with the potential to evolve from an acute infection to post-acute and long-COVID, which is still in the process of elucidation. Diagnostic and prognostic research is essential t...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2022-09-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/9/e061094.full |
| _version_ | 1811273815206920192 |
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| author | Luiz Augusto Facchini João Ricardo Nickenig Vissoci Débora Moura Maria Aparecida Salci Ligia Carreira Magda Lúcia Félix de Oliveira Rosana Rosseto de Oliveira Sueli Mitsumi Tsukuda Ichisato Eduardo Rocha Covre Giovanna Brichi Pesce Jéssica Adrielle Teixeira Santos Flávia Maria Derhun Anai Adario Hungaro Carla Franciele Höring Márcia Lorena Alves dos Santos Natan Nascimento de Oliveira Marcelle Paiano Herbert Leopoldo de Freitas Góes André Estevam Jaques Carlos Alexandre Molena Fernandes |
| author_facet | Luiz Augusto Facchini João Ricardo Nickenig Vissoci Débora Moura Maria Aparecida Salci Ligia Carreira Magda Lúcia Félix de Oliveira Rosana Rosseto de Oliveira Sueli Mitsumi Tsukuda Ichisato Eduardo Rocha Covre Giovanna Brichi Pesce Jéssica Adrielle Teixeira Santos Flávia Maria Derhun Anai Adario Hungaro Carla Franciele Höring Márcia Lorena Alves dos Santos Natan Nascimento de Oliveira Marcelle Paiano Herbert Leopoldo de Freitas Góes André Estevam Jaques Carlos Alexandre Molena Fernandes |
| author_sort | Luiz Augusto Facchini |
| collection | DOAJ |
| description | Introduction Since 2020, the world has been going through a viral pandemic with a high morbidity and mortality rate along with the potential to evolve from an acute infection to post-acute and long-COVID, which is still in the process of elucidation. Diagnostic and prognostic research is essential to understand the complexity of factors and contexts involving the illness’s process. This protocol introduces a study strategy to analyse predictors, sequelae, and repercussions of COVID-19 in adults and older adults with different disease severities in the State of Paraná, Brazil.Methods and analysis A mixed-methods sequential explanatory design. The quantitative data will be conducted by an ambispective cohort study, which will explore the manifestations of COVID-19 for 18 months, with nearly 3000 participants with confirmed diagnoses of COVID-19 (reverse transcription-PCR test) between March and December of 2020, retrieved from national disease reporting databases, over 18 years old, living in a Brazilian State (Paraná) and who survived the viral infection after being discharged from a health service. Data collection will be conducted through telephone interviews, at two different occasions: the first will be a recall 12 months after the acute phase as a retrospective follow-up, and the second will be another prospective interview, with data of the following 6 months. For the qualitative step, Grounded Theory will be used; participants will be selected from the cohort population. The first sample group will be composed of people who were discharged from the intensive care unit, and other sample groups will be composed according to theoretical saturation. The qualitative data will follow the temporal design and classification of the disease provided for in the cohort.Ethics and dissemination Ethics approval was granted by the State University of Maringá, under opinion number: 4 165 272 and CAAE: 34787020.0.0000.0104 on 21 July 2020, and Hospital do Trabalhador (Worker’s Hospital), which is accountable for the Health Department of the State of Paraná, under opinion number: 4 214 589 and CAAE: 34787020.0.3001.5225 on 15 August 2020. The participants will verbally consent to the research, their consent will be recorded, and the informed consent form will be sent by mail or email. Outcomes will be widely disseminated through peer-reviewed manuscripts, conference presentations, media and reports to related authorities. |
| first_indexed | 2024-04-12T23:05:59Z |
| format | Article |
| id | doaj.art-b69d0b4bff264424a01024ba51822ec9 |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-04-12T23:05:59Z |
| publishDate | 2022-09-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-b69d0b4bff264424a01024ba51822ec92022-12-22T03:12:54ZengBMJ Publishing GroupBMJ Open2044-60552022-09-0112910.1136/bmjopen-2022-061094Post-acute COVID and long-COVID among adults and older adults in the State of Paraná, Brazil: protocol for an ambispective cohort studyLuiz Augusto Facchini0João Ricardo Nickenig Vissoci1Débora Moura2Maria Aparecida Salci3Ligia Carreira4Magda Lúcia Félix de Oliveira5Rosana Rosseto de Oliveira6Sueli Mitsumi Tsukuda Ichisato7Eduardo Rocha Covre8Giovanna Brichi Pesce9Jéssica Adrielle Teixeira Santos10Flávia Maria Derhun11Anai Adario Hungaro12Carla Franciele Höring13Márcia Lorena Alves dos Santos14Natan Nascimento de Oliveira15Marcelle Paiano16Herbert Leopoldo de Freitas Góes17André Estevam Jaques18Carlos Alexandre Molena Fernandes19Departamento de Medicina Social, Universidade Federal de Pelotas, Pelotas, Rio Grande do Sul, BrazilDivision of Emergency Medicine, Duke University Medical Center, Durham, North Carolina, USANursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilNursing Department, Universidade Estadual de Maringá, Maringa, BrazilIntroduction Since 2020, the world has been going through a viral pandemic with a high morbidity and mortality rate along with the potential to evolve from an acute infection to post-acute and long-COVID, which is still in the process of elucidation. Diagnostic and prognostic research is essential to understand the complexity of factors and contexts involving the illness’s process. This protocol introduces a study strategy to analyse predictors, sequelae, and repercussions of COVID-19 in adults and older adults with different disease severities in the State of Paraná, Brazil.Methods and analysis A mixed-methods sequential explanatory design. The quantitative data will be conducted by an ambispective cohort study, which will explore the manifestations of COVID-19 for 18 months, with nearly 3000 participants with confirmed diagnoses of COVID-19 (reverse transcription-PCR test) between March and December of 2020, retrieved from national disease reporting databases, over 18 years old, living in a Brazilian State (Paraná) and who survived the viral infection after being discharged from a health service. Data collection will be conducted through telephone interviews, at two different occasions: the first will be a recall 12 months after the acute phase as a retrospective follow-up, and the second will be another prospective interview, with data of the following 6 months. For the qualitative step, Grounded Theory will be used; participants will be selected from the cohort population. The first sample group will be composed of people who were discharged from the intensive care unit, and other sample groups will be composed according to theoretical saturation. The qualitative data will follow the temporal design and classification of the disease provided for in the cohort.Ethics and dissemination Ethics approval was granted by the State University of Maringá, under opinion number: 4 165 272 and CAAE: 34787020.0.0000.0104 on 21 July 2020, and Hospital do Trabalhador (Worker’s Hospital), which is accountable for the Health Department of the State of Paraná, under opinion number: 4 214 589 and CAAE: 34787020.0.3001.5225 on 15 August 2020. The participants will verbally consent to the research, their consent will be recorded, and the informed consent form will be sent by mail or email. Outcomes will be widely disseminated through peer-reviewed manuscripts, conference presentations, media and reports to related authorities.https://bmjopen.bmj.com/content/12/9/e061094.full |
| spellingShingle | Luiz Augusto Facchini João Ricardo Nickenig Vissoci Débora Moura Maria Aparecida Salci Ligia Carreira Magda Lúcia Félix de Oliveira Rosana Rosseto de Oliveira Sueli Mitsumi Tsukuda Ichisato Eduardo Rocha Covre Giovanna Brichi Pesce Jéssica Adrielle Teixeira Santos Flávia Maria Derhun Anai Adario Hungaro Carla Franciele Höring Márcia Lorena Alves dos Santos Natan Nascimento de Oliveira Marcelle Paiano Herbert Leopoldo de Freitas Góes André Estevam Jaques Carlos Alexandre Molena Fernandes Post-acute COVID and long-COVID among adults and older adults in the State of Paraná, Brazil: protocol for an ambispective cohort study BMJ Open |
| title | Post-acute COVID and long-COVID among adults and older adults in the State of Paraná, Brazil: protocol for an ambispective cohort study |
| title_full | Post-acute COVID and long-COVID among adults and older adults in the State of Paraná, Brazil: protocol for an ambispective cohort study |
| title_fullStr | Post-acute COVID and long-COVID among adults and older adults in the State of Paraná, Brazil: protocol for an ambispective cohort study |
| title_full_unstemmed | Post-acute COVID and long-COVID among adults and older adults in the State of Paraná, Brazil: protocol for an ambispective cohort study |
| title_short | Post-acute COVID and long-COVID among adults and older adults in the State of Paraná, Brazil: protocol for an ambispective cohort study |
| title_sort | post acute covid and long covid among adults and older adults in the state of parana brazil protocol for an ambispective cohort study |
| url | https://bmjopen.bmj.com/content/12/9/e061094.full |
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