Nanographene oxide-methylene blue as phototherapies platform for breast tumor ablation and metastasis prevention in a syngeneic orthotopic murine model

Nanographene oxide-methylene blue as phototherapies platform for breast tumor ablation and metastasis prevention in a syngeneic orthotopic murine model

Abstract Background In the photodynamic therapy (PDT), the photosensitizer absorbs light and transfers the energy of the excited state to the oxygen in the cell environment producing reactive oxygen species (ROS), that in its turn, may cause cell damage. In the photothermal therapy (PTT), light also...

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Bibliographic Details
Main Authors: Mayara Simonelly Costa dos Santos, Ana Luisa Gouvêa, Ludmilla David de Moura, Leonardo Giordano Paterno, Paulo Eduardo Narcizo de Souza, Ana Paula Bastos, Emanuel Adelino Medeiros Damasceno, Fabiane Hiratsuka Veiga-Souza, Ricardo Bentes de Azevedo, Sônia Nair Báo
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Nanobiotechnology
Subjects:
Photodynamic therapy
Photothermal therapy
Graphene oxide
Photosensitizer dye
Bioluminescence
Tumor regression and metastasis avoidance
Online Access:http://link.springer.com/article/10.1186/s12951-018-0333-6

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