Genome-Wide Profiling of Transcriptome and DNA Methylome in Human Embryonic Stem Cells Exposed to Extractable Organic Matter from PM2.5

Increasing evidence indicates that PM2.5 exposure disrupts early embryonic development, but the mechanisms remain unclear. We hypothesized that PM2.5 cause abnormal embryonic development by interfering with DNA methylation and mRNA expression. In this study, we observed that human embryonic stem cel...

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Bibliographic Details
Main Authors: Jianming Wang, Tiantian Liu, Jin Wang, Tao Chen, Yan Jiang
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Toxics
Subjects:
Online Access:https://www.mdpi.com/2305-6304/11/10/840