Molecular and clonal evolution in vivo reveal a common pathway of distant relapse gliomas

Summary: The evolutionary trajectories of genomic alterations underlying distant recurrence in glioma remain largely unknown. To elucidate glioma evolution, we analyzed the evolutionary trajectories of matched pairs of primary tumors and relapse tumors or tumor in situ fluid (TISF) based on deep who...

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Bibliographic Details
Main Authors: Guanzheng Liu, Chaojie Bu, Guangzhong Guo, Zhiyue Zhang, Zhiyuan Sheng, Kaiyuan Deng, Shuang Wu, Sensen Xu, Yage Bu, Yushuai Gao, Meiyun Wang, Gang Liu, Lingfei Kong, Tianxiao Li, Ming Li, Xingyao Bu
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S258900422301605X