From Inflammasome to Exosome—Does Extracellular Vesicle Secretion Constitute an Inflammasome-Dependent Immune Response?

From Inflammasome to Exosome—Does Extracellular Vesicle Secretion Constitute an Inflammasome-Dependent Immune Response?

Inflammasomes are intracellular protein complexes of pattern recognition receptors and caspase-1, with essential functions in regulating inflammatory responses of macrophages and dendritic cells. The primary role of inflammasomes is to catalyze processing and secretion of pro-inflammatory cytokines...

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Bibliographic Details
Main Authors: Wojciech Cypryk, Tuula A. Nyman, Sampsa Matikainen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
inflammasome
inflammation
extracellular vesicle (EV)
signaling
EV
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02188/full

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