Minimally Invasive Treatment Options for Hepatic Uveal Melanoma Metastases
Uveal melanoma is one of the most common primary intraocular malignancies that accounts for about 85% of all ocular melanomas. The pathophysiology of uveal melanoma is distinct from cutaneous melanoma and has separate tumor profiles. The management of uveal melanoma is largely dependent on the prese...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Diagnostics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4418/13/11/1836 |
| _version_ | 1827739696113909760 |
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| author | Abin Sajan Samuel Fordyce Andrew Sideris Connie Liou Zeeshan Toor John Filtes Venkatesh Krishnasamy Noor Ahmad Stephen Reis Sidney Brejt Asad Baig Shaheer Khan Michael Caplan David Sperling Joshua Weintraub |
| author_facet | Abin Sajan Samuel Fordyce Andrew Sideris Connie Liou Zeeshan Toor John Filtes Venkatesh Krishnasamy Noor Ahmad Stephen Reis Sidney Brejt Asad Baig Shaheer Khan Michael Caplan David Sperling Joshua Weintraub |
| author_sort | Abin Sajan |
| collection | DOAJ |
| description | Uveal melanoma is one of the most common primary intraocular malignancies that accounts for about 85% of all ocular melanomas. The pathophysiology of uveal melanoma is distinct from cutaneous melanoma and has separate tumor profiles. The management of uveal melanoma is largely dependent on the presence of metastases, which confers a poor prognosis with a one-year survival reaching only 15%. Although a better understanding of tumor biology has led to the development of novel pharmacologic agents, there is increasing demand for minimally invasive management of hepatic uveal melanoma metastases. Multiple studies have already summarized the systemic therapeutic options available for metastatic uveal melanoma. This review covers the current research for the most prevalent locoregional treatment options for metastatic uveal melanoma including percutaneous hepatic perfusion, immunoembolization, chemoembolization, thermal ablation, and radioembolization. |
| first_indexed | 2024-03-11T03:09:50Z |
| format | Article |
| id | doaj.art-b6b121b5196f428697af934f9757a4e6 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T03:09:50Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-b6b121b5196f428697af934f9757a4e62023-11-18T07:41:47ZengMDPI AGDiagnostics2075-44182023-05-011311183610.3390/diagnostics13111836Minimally Invasive Treatment Options for Hepatic Uveal Melanoma MetastasesAbin Sajan0Samuel Fordyce1Andrew Sideris2Connie Liou3Zeeshan Toor4John Filtes5Venkatesh Krishnasamy6Noor Ahmad7Stephen Reis8Sidney Brejt9Asad Baig10Shaheer Khan11Michael Caplan12David Sperling13Joshua Weintraub14Department of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USADepartment of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USADepartment of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USADepartment of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USADepartment of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USADepartment of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USADepartment of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USADepartment of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USADepartment of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USADepartment of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USADepartment of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USADepartment of Medicine, Columbia University Medical Center, 161 Fort Washington Avenue, New York, NY 10032, USADepartment of Medicine, Columbia University Medical Center, 161 Fort Washington Avenue, New York, NY 10032, USADepartment of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USADepartment of Radiology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USAUveal melanoma is one of the most common primary intraocular malignancies that accounts for about 85% of all ocular melanomas. The pathophysiology of uveal melanoma is distinct from cutaneous melanoma and has separate tumor profiles. The management of uveal melanoma is largely dependent on the presence of metastases, which confers a poor prognosis with a one-year survival reaching only 15%. Although a better understanding of tumor biology has led to the development of novel pharmacologic agents, there is increasing demand for minimally invasive management of hepatic uveal melanoma metastases. Multiple studies have already summarized the systemic therapeutic options available for metastatic uveal melanoma. This review covers the current research for the most prevalent locoregional treatment options for metastatic uveal melanoma including percutaneous hepatic perfusion, immunoembolization, chemoembolization, thermal ablation, and radioembolization.https://www.mdpi.com/2075-4418/13/11/1836uveal melanomaliver metastasesinterventional radiologylocoregional therapy |
| spellingShingle | Abin Sajan Samuel Fordyce Andrew Sideris Connie Liou Zeeshan Toor John Filtes Venkatesh Krishnasamy Noor Ahmad Stephen Reis Sidney Brejt Asad Baig Shaheer Khan Michael Caplan David Sperling Joshua Weintraub Minimally Invasive Treatment Options for Hepatic Uveal Melanoma Metastases Diagnostics uveal melanoma liver metastases interventional radiology locoregional therapy |
| title | Minimally Invasive Treatment Options for Hepatic Uveal Melanoma Metastases |
| title_full | Minimally Invasive Treatment Options for Hepatic Uveal Melanoma Metastases |
| title_fullStr | Minimally Invasive Treatment Options for Hepatic Uveal Melanoma Metastases |
| title_full_unstemmed | Minimally Invasive Treatment Options for Hepatic Uveal Melanoma Metastases |
| title_short | Minimally Invasive Treatment Options for Hepatic Uveal Melanoma Metastases |
| title_sort | minimally invasive treatment options for hepatic uveal melanoma metastases |
| topic | uveal melanoma liver metastases interventional radiology locoregional therapy |
| url | https://www.mdpi.com/2075-4418/13/11/1836 |
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