Molecular Basis of Complement C1q Collagen-Like Region Interaction with the Immunoglobulin-Like Receptor LAIR-1

Molecular Basis of Complement C1q Collagen-Like Region Interaction with the Immunoglobulin-Like Receptor LAIR-1

The immune system homeostasis relies on a tight equilibrium of interconnected stimulatory and inhibitory signals. Disruption of this balance is characteristic of autoimmune diseases such as systemic lupus erythematosus (SLE). Aside from activating the classical complement pathway and enhancing patho...

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Bibliographic Details
Main Authors: Guillaume Fouët, Isabelle Bally, Anne Chouquet, Jean-Baptiste Reiser, Nicole M. Thielens, Christine Gaboriaud, Véronique Rossi
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
immune tolerance
immunoglobin-like receptor
complement C1q
collagen-like region
Online Access:https://www.mdpi.com/1422-0067/22/10/5125

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