When benign leiomyomas metastasize to the lungs - a case report
Benign metastasizing leiomyoma is a rare disease occurring mainly in premenopausal women with a history of uterine leiomyoma, which is most commonly characterized by pulmonary metastases. The pathogenesis of this condition is poorly understood. Usually patients are asymptomatic or present unspecifi...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2023-02-01
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| Series: | Monaldi Archives for Chest Disease |
| Subjects: | |
| Online Access: | https://www.monaldi-archives.org/index.php/macd/article/view/2488 |
| _version_ | 1811173113334857728 |
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| author | Joana Vieira Naia Diana Pimenta Anita Paiva Rita Costa Conceição Souto de Moura Raquel Pereira João Filipe Cruz |
| author_facet | Joana Vieira Naia Diana Pimenta Anita Paiva Rita Costa Conceição Souto de Moura Raquel Pereira João Filipe Cruz |
| author_sort | Joana Vieira Naia |
| collection | DOAJ |
| description |
Benign metastasizing leiomyoma is a rare disease occurring mainly in premenopausal women with a history of uterine leiomyoma, which is most commonly characterized by pulmonary metastases. The pathogenesis of this condition is poorly understood. Usually patients are asymptomatic or present unspecific symptoms. Pathological examination combined with immunohistochemistry is essential for the diagnosis. Treatment depends on the age, hormonal status, symptoms and extent of the lesions, with surgical resection being the most effective treatment. We report the case of a 72-year-old woman with a history of total hysterectomy due to myomas 30 years earlier that presented persistent dry cough. Her chest computed tomography revealed multiple small nodules in the pulmonary parenchyma. Given the small dimensions and difficult accessibility of the nodules, surgical biopsy was made for histopathological examination and immunohistochemical staining, which were compatible with metastasizing leiomyoma. Treatment with letrozole was initiated and well tolerated.
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| first_indexed | 2024-04-10T17:41:25Z |
| format | Article |
| id | doaj.art-b6b1dd852db744ebbab2ca86bb78edf8 |
| institution | Directory Open Access Journal |
| issn | 1122-0643 2532-5264 |
| language | English |
| last_indexed | 2024-04-10T17:41:25Z |
| publishDate | 2023-02-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Monaldi Archives for Chest Disease |
| spelling | doaj.art-b6b1dd852db744ebbab2ca86bb78edf82023-02-03T12:29:19ZengPAGEPress PublicationsMonaldi Archives for Chest Disease1122-06432532-52642023-02-0110.4081/monaldi.2023.2488When benign leiomyomas metastasize to the lungs - a case reportJoana Vieira Naia0Diana Pimenta1Anita Paiva2Rita Costa3Conceição Souto de Moura4Raquel Pereira5João Filipe Cruz6Pulmonology Department, Hospital of BragaPulmonology Department, Hospital of BragaPulmonology Department, Hospital of BragaThoracic Surgery Department, University Hospital Center of São João, PortoPathology Department, University Hospital Center of São João, PortoPulmonology Department, Hospital of BragaPulmonology Department, Hospital of Braga Benign metastasizing leiomyoma is a rare disease occurring mainly in premenopausal women with a history of uterine leiomyoma, which is most commonly characterized by pulmonary metastases. The pathogenesis of this condition is poorly understood. Usually patients are asymptomatic or present unspecific symptoms. Pathological examination combined with immunohistochemistry is essential for the diagnosis. Treatment depends on the age, hormonal status, symptoms and extent of the lesions, with surgical resection being the most effective treatment. We report the case of a 72-year-old woman with a history of total hysterectomy due to myomas 30 years earlier that presented persistent dry cough. Her chest computed tomography revealed multiple small nodules in the pulmonary parenchyma. Given the small dimensions and difficult accessibility of the nodules, surgical biopsy was made for histopathological examination and immunohistochemical staining, which were compatible with metastasizing leiomyoma. Treatment with letrozole was initiated and well tolerated. https://www.monaldi-archives.org/index.php/macd/article/view/2488Benign metastasizing leiomyoma (BML)pulmonary nodulesmyomectomy |
| spellingShingle | Joana Vieira Naia Diana Pimenta Anita Paiva Rita Costa Conceição Souto de Moura Raquel Pereira João Filipe Cruz When benign leiomyomas metastasize to the lungs - a case report Monaldi Archives for Chest Disease Benign metastasizing leiomyoma (BML) pulmonary nodules myomectomy |
| title | When benign leiomyomas metastasize to the lungs - a case report |
| title_full | When benign leiomyomas metastasize to the lungs - a case report |
| title_fullStr | When benign leiomyomas metastasize to the lungs - a case report |
| title_full_unstemmed | When benign leiomyomas metastasize to the lungs - a case report |
| title_short | When benign leiomyomas metastasize to the lungs - a case report |
| title_sort | when benign leiomyomas metastasize to the lungs a case report |
| topic | Benign metastasizing leiomyoma (BML) pulmonary nodules myomectomy |
| url | https://www.monaldi-archives.org/index.php/macd/article/view/2488 |
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