PD-1 checkpoint blockade in advanced melanoma patients: NK cells, monocytic subsets and host PD-L1 expression as predictive biomarker candidates

PD-1 checkpoint blockade in advanced melanoma patients: NK cells, monocytic subsets and host PD-L1 expression as predictive biomarker candidates

Blockade of the PD-1 receptor has revolutionized the treatment of metastatic melanoma, with significant increases in overall survival (OS) and a dramatic improvement in patient quality of life. Despite the success of this approach, the number of benefitting patients is limited and there is a need fo...

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Bibliographic Details
Main Authors: Yago Pico de Coaña, Maria Wolodarski, Irene van der Haar Àvila, Takahiro Nakajima, Stamatina Rentouli, Andreas Lundqvist, Giuseppe Masucci, Johan Hansson, Rolf Kiessling
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
melanoma
immune checkpoint inhibitors
mdscs
nk cells
predictive biomarkers
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1786888

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