Single-Dose Cisplatin Pre-Treatment Enhances Efficacy of ROBO1-Targeted Radioimmunotherapy

Single-Dose Cisplatin Pre-Treatment Enhances Efficacy of ROBO1-Targeted Radioimmunotherapy

We previously reported that radioimmunotherapy (RIT) using <sup>90</sup>Y-labeled anti-ROBO1 IgG (<sup>90</sup>Y-B5209B) achieved significant anti-tumor effects against small-cell lung cancer (SCLC) xenografts. However, subsequent tumor regrowth suggested the necessity for mo...

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Bibliographic Details
Main Authors: Kentaro Fujiwara, Keitaro Koyama, Atsushi B. Tsuji, Hiroko Iwanari, Osamu Kusano-Arai, Tatsuya Higashi, Toshimitsu Momose, Takao Hamakubo
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
radioimmunotherapy
cisplatin
combination therapy
small-cell lung cancer
ROBO1
Online Access:https://www.mdpi.com/1422-0067/21/20/7728

Internet

https://www.mdpi.com/1422-0067/21/20/7728

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