Physioxia Expanded Bone Marrow Derived Mesenchymal Stem Cells Have Improved Cartilage Repair in an Early Osteoarthritic Focal Defect Model

Physioxia Expanded Bone Marrow Derived Mesenchymal Stem Cells Have Improved Cartilage Repair in an Early Osteoarthritic Focal Defect Model

Focal early osteoarthritis (OA) or degenerative lesions account for 60% of treated cartilage defects each year. The current cell-based regenerative treatments have an increased failure rate for treating degenerative lesions compared to traumatic defects. Mesenchymal stem cells (MSCs) are an alternat...

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Bibliographic Details
Main Authors: Girish Pattappa, Jonas Krueckel, Ruth Schewior, Dustin Franke, Alexander Mench, Matthias Koch, Johannes Weber, Siegmund Lang, Christian G. Pfeifer, Brian Johnstone, Denitsa Docheva, Volker Alt, Peter Angele, Johannes Zellner
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biology
Subjects:
mesenchymal stem cells
chondrogenesis
hypoxia
cartilage
early osteoarthritis
Online Access:https://www.mdpi.com/2079-7737/9/8/230

Internet

https://www.mdpi.com/2079-7737/9/8/230

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