Nasal Methicillin Resistant Staphylococcus aureus Associated Post-surgical Wounds Infections
Aims: Staphylococcus aureus nasal colonization is an important risk factor for developing a wide range of infections in clinical setting. This study was aimed at determining the extent of staphylococcal carriages including methicillin resistant Staphylococcus aureus (MRSA) in post-surgical patients...
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| Format: | Article |
| Language: | English |
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Malaysian Society for Microbiology
2012-01-01
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| Series: | Malaysian Journal of Microbiology |
| Subjects: | |
| Online Access: | http://web.usm.my/mjm/issues/vol8no4/Short%204.pdf |
| _version_ | 1818670290161369088 |
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| author | Ikpeme, E. M. Enyi-Idoh, K. H. Nfongeh, J. F. Etim, L. B. Akubuenyi, F. C. |
| author_facet | Ikpeme, E. M. Enyi-Idoh, K. H. Nfongeh, J. F. Etim, L. B. Akubuenyi, F. C. |
| author_sort | Ikpeme, E. M. |
| collection | DOAJ |
| description | Aims: Staphylococcus aureus nasal colonization is an important risk factor for developing a wide range of infections in clinical setting. This study was aimed at determining the extent of staphylococcal carriages including methicillin resistant Staphylococcus aureus (MRSA) in post-surgical patients and employees in a tertiary health facility. Methodology and Results: Between April and July 2010, 240 post-surgical patients and 80 hospital personnel at the University of Calabar Teaching Hospital, Calabar were enrolled in the present study. All subjects consented to participation in the study and those who had previous medical history or treatment on antibiotic in the last six months prior to enrolment were noted. Nasal specimens collected from carrier and post-surgical sites in individuals (15-63 years) who were hospitalized for at least 21 days were immediately placed in Staurts’ transport medium and kept at 4 °C before being analyzed accordingly and screened for methicillin resistant Staphylococcus aureus. Out of a total number of 320 subjects examined within a period of 4 months 144 (45%) were carriers of Staphylococcus aureus and 55 (38%) of these were MRSA. Demographic and clinical data of subjects indicated more male carriers (60.7%) confined to older age groups above 35 years. There was a significant difference (p> 0.05) in Staphylococcus aureus carriage for subjects with recent medical history of hospitalization or treatment with antibiotics. There also appears to be a considerable association (50.9%) between nasal carriage status and autoinfection of post-surgical wounds. A good proportion of all strains tested were resistant to commonly used antibiotics. Approximately 89% of MRSA were resistant to penicillin. Resistant rate against other antibiotics was largely below 30%. Conclusion, significance and impact of study: An improved understanding of nasal carriage is needed to foster development of new strategies to reduce colonization and subsequent infection with bacteria. |
| first_indexed | 2024-12-17T07:05:45Z |
| format | Article |
| id | doaj.art-b6b5bf58fdf4409b95b39439a42038f9 |
| institution | Directory Open Access Journal |
| issn | 1823-8262 2231-7538 |
| language | English |
| last_indexed | 2024-12-17T07:05:45Z |
| publishDate | 2012-01-01 |
| publisher | Malaysian Society for Microbiology |
| record_format | Article |
| series | Malaysian Journal of Microbiology |
| spelling | doaj.art-b6b5bf58fdf4409b95b39439a42038f92022-12-21T21:59:09ZengMalaysian Society for MicrobiologyMalaysian Journal of Microbiology1823-82622231-75382012-01-0184298300Nasal Methicillin Resistant Staphylococcus aureus Associated Post-surgical Wounds InfectionsIkpeme, E. M.Enyi-Idoh, K. H.Nfongeh, J. F.Etim, L. B.Akubuenyi, F. C.Aims: Staphylococcus aureus nasal colonization is an important risk factor for developing a wide range of infections in clinical setting. This study was aimed at determining the extent of staphylococcal carriages including methicillin resistant Staphylococcus aureus (MRSA) in post-surgical patients and employees in a tertiary health facility. Methodology and Results: Between April and July 2010, 240 post-surgical patients and 80 hospital personnel at the University of Calabar Teaching Hospital, Calabar were enrolled in the present study. All subjects consented to participation in the study and those who had previous medical history or treatment on antibiotic in the last six months prior to enrolment were noted. Nasal specimens collected from carrier and post-surgical sites in individuals (15-63 years) who were hospitalized for at least 21 days were immediately placed in Staurts’ transport medium and kept at 4 °C before being analyzed accordingly and screened for methicillin resistant Staphylococcus aureus. Out of a total number of 320 subjects examined within a period of 4 months 144 (45%) were carriers of Staphylococcus aureus and 55 (38%) of these were MRSA. Demographic and clinical data of subjects indicated more male carriers (60.7%) confined to older age groups above 35 years. There was a significant difference (p> 0.05) in Staphylococcus aureus carriage for subjects with recent medical history of hospitalization or treatment with antibiotics. There also appears to be a considerable association (50.9%) between nasal carriage status and autoinfection of post-surgical wounds. A good proportion of all strains tested were resistant to commonly used antibiotics. Approximately 89% of MRSA were resistant to penicillin. Resistant rate against other antibiotics was largely below 30%. Conclusion, significance and impact of study: An improved understanding of nasal carriage is needed to foster development of new strategies to reduce colonization and subsequent infection with bacteria.http://web.usm.my/mjm/issues/vol8no4/Short%204.pdfNasal Staphylococcus aureusmethicillin resistance |
| spellingShingle | Ikpeme, E. M. Enyi-Idoh, K. H. Nfongeh, J. F. Etim, L. B. Akubuenyi, F. C. Nasal Methicillin Resistant Staphylococcus aureus Associated Post-surgical Wounds Infections Malaysian Journal of Microbiology Nasal Staphylococcus aureus methicillin resistance |
| title | Nasal Methicillin Resistant Staphylococcus aureus Associated Post-surgical Wounds Infections |
| title_full | Nasal Methicillin Resistant Staphylococcus aureus Associated Post-surgical Wounds Infections |
| title_fullStr | Nasal Methicillin Resistant Staphylococcus aureus Associated Post-surgical Wounds Infections |
| title_full_unstemmed | Nasal Methicillin Resistant Staphylococcus aureus Associated Post-surgical Wounds Infections |
| title_short | Nasal Methicillin Resistant Staphylococcus aureus Associated Post-surgical Wounds Infections |
| title_sort | nasal methicillin resistant staphylococcus aureus associated post surgical wounds infections |
| topic | Nasal Staphylococcus aureus methicillin resistance |
| url | http://web.usm.my/mjm/issues/vol8no4/Short%204.pdf |
| work_keys_str_mv | AT ikpemeem nasalmethicillinresistantstaphylococcusaureusassociatedpostsurgicalwoundsinfections AT enyiidohkh nasalmethicillinresistantstaphylococcusaureusassociatedpostsurgicalwoundsinfections AT nfongehjf nasalmethicillinresistantstaphylococcusaureusassociatedpostsurgicalwoundsinfections AT etimlb nasalmethicillinresistantstaphylococcusaureusassociatedpostsurgicalwoundsinfections AT akubuenyifc nasalmethicillinresistantstaphylococcusaureusassociatedpostsurgicalwoundsinfections |