NEFOPAM IN THE STRUCTURE OF PERIOPERATIVE MULTIMODAL ANALGESIA IN PATIENTS WITH LUMBAR DISC HERNIATION: PRELIMINARY RESULTS
PURPOSE OF THE STUDY. To compare efficacy and safety of nefopam and paracetamol as components of the preventive multimodal anesthesia (PMA) in patients operated on for a hernia of an intervertebral disc (hID).MATERIAL AND METHODS. In 2013, 35 patients were operated on for hID. Group 1 (21) received...
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| Format: | Article |
| Language: | Russian |
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Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department
2016-03-01
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| Series: | Неотложная медицинская помощь |
| Subjects: | |
| Online Access: | https://www.jnmp.ru/jour/article/view/220 |
| _version_ | 1797758118128517120 |
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| author | P. G. Genov V. Kh. Timerbayev A. A. Grin |
| author_facet | P. G. Genov V. Kh. Timerbayev A. A. Grin |
| author_sort | P. G. Genov |
| collection | DOAJ |
| description | PURPOSE OF THE STUDY. To compare efficacy and safety of nefopam and paracetamol as components of the preventive multimodal anesthesia (PMA) in patients operated on for a hernia of an intervertebral disc (hID).MATERIAL AND METHODS. In 2013, 35 patients were operated on for hID. Group 1 (21) received PMA including wound infiltration by bupivacaine, ketoprofen and paracetamol. Group 2 (15) received nefopam instead of paracetamol. Intensity of postoperative pain, side effects and satisfaction of patients with anesthesia were assessed, and in 6 months later — existence and intensity of chronic pain.RESULTS. Intensity of postoperative pain, satisfaction with anesthesia, and also frequency and intensity of chronic pain didn’t differ in group 1 and 2. Occurrence of undesirable reactions was higher in group 2.CONCLUSION. In patients receiving nefopam and paracetamol as components of PMA, intensity of postoperative pain and also occurence and intensity of chronic pain don’t differ, but the patients receiving to nefopam, experience the undesirable reactions more often which do not affect satisfaction with anesthesia. |
| first_indexed | 2024-03-12T18:25:24Z |
| format | Article |
| id | doaj.art-b6b67166a12a40a58d605b9f9e177d74 |
| institution | Directory Open Access Journal |
| issn | 2223-9022 2541-8017 |
| language | Russian |
| last_indexed | 2024-03-12T18:25:24Z |
| publishDate | 2016-03-01 |
| publisher | Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department |
| record_format | Article |
| series | Неотложная медицинская помощь |
| spelling | doaj.art-b6b67166a12a40a58d605b9f9e177d742023-08-02T08:34:47ZrusSklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare DepartmentНеотложная медицинская помощь2223-90222541-80172016-03-01031115218NEFOPAM IN THE STRUCTURE OF PERIOPERATIVE MULTIMODAL ANALGESIA IN PATIENTS WITH LUMBAR DISC HERNIATION: PRELIMINARY RESULTSP. G. Genov0V. Kh. Timerbayev1A. A. Grin2N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, MoscowN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, MoscowN.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, MoscowPURPOSE OF THE STUDY. To compare efficacy and safety of nefopam and paracetamol as components of the preventive multimodal anesthesia (PMA) in patients operated on for a hernia of an intervertebral disc (hID).MATERIAL AND METHODS. In 2013, 35 patients were operated on for hID. Group 1 (21) received PMA including wound infiltration by bupivacaine, ketoprofen and paracetamol. Group 2 (15) received nefopam instead of paracetamol. Intensity of postoperative pain, side effects and satisfaction of patients with anesthesia were assessed, and in 6 months later — existence and intensity of chronic pain.RESULTS. Intensity of postoperative pain, satisfaction with anesthesia, and also frequency and intensity of chronic pain didn’t differ in group 1 and 2. Occurrence of undesirable reactions was higher in group 2.CONCLUSION. In patients receiving nefopam and paracetamol as components of PMA, intensity of postoperative pain and also occurence and intensity of chronic pain don’t differ, but the patients receiving to nefopam, experience the undesirable reactions more often which do not affect satisfaction with anesthesia.https://www.jnmp.ru/jour/article/view/220removal of an intervertebral disc herniaspinal surgerypostoperative anesthesiamultimodal anesthesiapostoperative painnefopamparacetamol |
| spellingShingle | P. G. Genov V. Kh. Timerbayev A. A. Grin NEFOPAM IN THE STRUCTURE OF PERIOPERATIVE MULTIMODAL ANALGESIA IN PATIENTS WITH LUMBAR DISC HERNIATION: PRELIMINARY RESULTS Неотложная медицинская помощь removal of an intervertebral disc hernia spinal surgery postoperative anesthesia multimodal anesthesia postoperative pain nefopam paracetamol |
| title | NEFOPAM IN THE STRUCTURE OF PERIOPERATIVE MULTIMODAL ANALGESIA IN PATIENTS WITH LUMBAR DISC HERNIATION: PRELIMINARY RESULTS |
| title_full | NEFOPAM IN THE STRUCTURE OF PERIOPERATIVE MULTIMODAL ANALGESIA IN PATIENTS WITH LUMBAR DISC HERNIATION: PRELIMINARY RESULTS |
| title_fullStr | NEFOPAM IN THE STRUCTURE OF PERIOPERATIVE MULTIMODAL ANALGESIA IN PATIENTS WITH LUMBAR DISC HERNIATION: PRELIMINARY RESULTS |
| title_full_unstemmed | NEFOPAM IN THE STRUCTURE OF PERIOPERATIVE MULTIMODAL ANALGESIA IN PATIENTS WITH LUMBAR DISC HERNIATION: PRELIMINARY RESULTS |
| title_short | NEFOPAM IN THE STRUCTURE OF PERIOPERATIVE MULTIMODAL ANALGESIA IN PATIENTS WITH LUMBAR DISC HERNIATION: PRELIMINARY RESULTS |
| title_sort | nefopam in the structure of perioperative multimodal analgesia in patients with lumbar disc herniation preliminary results |
| topic | removal of an intervertebral disc hernia spinal surgery postoperative anesthesia multimodal anesthesia postoperative pain nefopam paracetamol |
| url | https://www.jnmp.ru/jour/article/view/220 |
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