Association of maxillary dental developmental abnormality with precocious puberty: a case-control study
Abstract Background Dental studies of precocious puberty have focused on examination of jaw and dentition growth. The aim of the study was to analyze the relationship between precocious puberty and maxillary dental developmental abnormalities (DDAs). Methods This retrospective study was conducted on...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2020-08-01
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| Series: | Maxillofacial Plastic and Reconstructive Surgery |
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| Online Access: | http://link.springer.com/article/10.1186/s40902-020-00274-3 |
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| author | Yesel Kim Nam-Ki Lee Jae Hyun Kim Jeong-Kui Ku Bu-Kyu Lee Hoi-In Jung Sun-Kyu Choi |
| author_facet | Yesel Kim Nam-Ki Lee Jae Hyun Kim Jeong-Kui Ku Bu-Kyu Lee Hoi-In Jung Sun-Kyu Choi |
| author_sort | Yesel Kim |
| collection | DOAJ |
| description | Abstract Background Dental studies of precocious puberty have focused on examination of jaw and dentition growth. The aim of the study was to analyze the relationship between precocious puberty and maxillary dental developmental abnormalities (DDAs). Methods This retrospective study was conducted on the Korean patients in whom dental panoramic and hand-wrist radiographs had been taken before they were 15 years of age. The maxillary DDAs were assessed as mesiodens, congenital missing teeth, peg-shape lateral incisors, or impacted teeth. The chronological ages of the control group members were within the normal range of the hand-wrist bone age. Others with a peak luteinizing hormone of ≥ 5 and < 5 IU/L were allocated to central precocious puberty (CPP) and peripheral precocious puberty (PPP), respectively. Results Of the enrolled 270 patients, 195, 52, and 23 were allocated to the control, CPP, and PPP groups, respectively. The maxillary DDAs were significantly more prevalent in the CPP group than in the other groups. Among those with maxillary DDA, the mesiodens predominated. Age- and sex-adjusted multivariate analysis revealed maxillary DDA (odds ratio, 3.36; 95% CI, 1.60-7.05) and especially mesiodens (odds ratio, 5.52; CI, 2.29-13.28) to be significantly associated with CPP. Conclusions Maxillary DDAs were significantly more prevalent in the CPP group than in the PPP or control groups. Among the many types of maxillary DDAs, mesiodens was significantly associated with CPP and may be considered a predictor of the development of CPP. |
| first_indexed | 2024-12-12T22:45:49Z |
| format | Article |
| id | doaj.art-b6b7e8dc23a84b5988572822e529df14 |
| institution | Directory Open Access Journal |
| issn | 2288-8586 |
| language | English |
| last_indexed | 2024-12-12T22:45:49Z |
| publishDate | 2020-08-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Maxillofacial Plastic and Reconstructive Surgery |
| spelling | doaj.art-b6b7e8dc23a84b5988572822e529df142022-12-22T00:09:13ZengSpringerOpenMaxillofacial Plastic and Reconstructive Surgery2288-85862020-08-014211710.1186/s40902-020-00274-3Association of maxillary dental developmental abnormality with precocious puberty: a case-control studyYesel Kim0Nam-Ki Lee1Jae Hyun Kim2Jeong-Kui Ku3Bu-Kyu Lee4Hoi-In Jung5Sun-Kyu Choi6Department of Preventive Dentistry and Public Oral Health, Yonsei UniversityDepartment of Orthodontics, Section of Dentistry, Seoul National University Bundang HospitalDepartment of Pediatrics, Seoul National University Bundang HospitalDepartment of Oral and Maxillofacial Surgery, Section of Dentistry, Armed Forces Medical Command, Armed Forces Capital Dental HospitalDepartment of Oral and Maxillofacial Surgery, Seoul Asan Medical CenterDepartment of Preventive Dentistry and Public Oral Health, Yonsei UniversityDepartment of Biostatistics, Korea University College of MedicineAbstract Background Dental studies of precocious puberty have focused on examination of jaw and dentition growth. The aim of the study was to analyze the relationship between precocious puberty and maxillary dental developmental abnormalities (DDAs). Methods This retrospective study was conducted on the Korean patients in whom dental panoramic and hand-wrist radiographs had been taken before they were 15 years of age. The maxillary DDAs were assessed as mesiodens, congenital missing teeth, peg-shape lateral incisors, or impacted teeth. The chronological ages of the control group members were within the normal range of the hand-wrist bone age. Others with a peak luteinizing hormone of ≥ 5 and < 5 IU/L were allocated to central precocious puberty (CPP) and peripheral precocious puberty (PPP), respectively. Results Of the enrolled 270 patients, 195, 52, and 23 were allocated to the control, CPP, and PPP groups, respectively. The maxillary DDAs were significantly more prevalent in the CPP group than in the other groups. Among those with maxillary DDA, the mesiodens predominated. Age- and sex-adjusted multivariate analysis revealed maxillary DDA (odds ratio, 3.36; 95% CI, 1.60-7.05) and especially mesiodens (odds ratio, 5.52; CI, 2.29-13.28) to be significantly associated with CPP. Conclusions Maxillary DDAs were significantly more prevalent in the CPP group than in the PPP or control groups. Among the many types of maxillary DDAs, mesiodens was significantly associated with CPP and may be considered a predictor of the development of CPP.http://link.springer.com/article/10.1186/s40902-020-00274-3Dental developmental abnormalityGonadotropin-releasing hormoneMesiodensPrecocious pubertySupernumerary tooth |
| spellingShingle | Yesel Kim Nam-Ki Lee Jae Hyun Kim Jeong-Kui Ku Bu-Kyu Lee Hoi-In Jung Sun-Kyu Choi Association of maxillary dental developmental abnormality with precocious puberty: a case-control study Maxillofacial Plastic and Reconstructive Surgery Dental developmental abnormality Gonadotropin-releasing hormone Mesiodens Precocious puberty Supernumerary tooth |
| title | Association of maxillary dental developmental abnormality with precocious puberty: a case-control study |
| title_full | Association of maxillary dental developmental abnormality with precocious puberty: a case-control study |
| title_fullStr | Association of maxillary dental developmental abnormality with precocious puberty: a case-control study |
| title_full_unstemmed | Association of maxillary dental developmental abnormality with precocious puberty: a case-control study |
| title_short | Association of maxillary dental developmental abnormality with precocious puberty: a case-control study |
| title_sort | association of maxillary dental developmental abnormality with precocious puberty a case control study |
| topic | Dental developmental abnormality Gonadotropin-releasing hormone Mesiodens Precocious puberty Supernumerary tooth |
| url | http://link.springer.com/article/10.1186/s40902-020-00274-3 |
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