The Role of Acyl-CoA Synthetase 1 in Bioactive Lipid Accumulation and the Development of Hepatic Insulin Resistance

The Role of Acyl-CoA Synthetase 1 in Bioactive Lipid Accumulation and the Development of Hepatic Insulin Resistance

The liver plays a crucial role in glucose metabolism. Obesity and a diet rich in fats (HFD) contribute to the accumulation of intracellular lipids. The aim of the study was to explore the involvement of acyl-CoA synthetase 1 (ACSL1) in bioactive lipid accumulation and the induction of liver insulin...

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Bibliographic Details
Main Authors: Piotr Zabielski, Monika Imierska, Kamila Roszczyc-Owsiejczuk, Mariusz Kuźmicki, Paweł Rogalski, Jarosław Daniluk, Agnieszka U. Błachnio-Zabielska
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Nutrients
Subjects:
liver
insulin resistance
obesity
high-fat diet
lipids
gene silencing
Online Access:https://www.mdpi.com/2072-6643/16/7/1003

Internet

https://www.mdpi.com/2072-6643/16/7/1003

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