Biobanking in dentistry: A review
Biobanks are not-for-profit services for the collection, processing, storage and distribution of biological samples and data for research and diagnostic purposes. In dentistry, biological materials and data obtained from questionnaires investigating oral conditions can be stored and used for large-s...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-11-01
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| Series: | Japanese Dental Science Review |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1882761621000454 |
| _version_ | 1797977765369085952 |
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| author | Stefano Sivolella Anna Scanu Zijing Xie Sara Vianello Edoardo Stellini |
| author_facet | Stefano Sivolella Anna Scanu Zijing Xie Sara Vianello Edoardo Stellini |
| author_sort | Stefano Sivolella |
| collection | DOAJ |
| description | Biobanks are not-for-profit services for the collection, processing, storage and distribution of biological samples and data for research and diagnostic purposes. In dentistry, biological materials and data obtained from questionnaires investigating oral conditions can be stored and used for large-scale studies on oral and systemic diseases. To give some examples: gene expression microarrays obtained on biobanked specimens were used in the identification of genetic alterations in oral cancer; efforts to identify genetic mechanisms behind dental caries have been based on an integrative analysis of transcriptome-wide associations and messenger RNA expression. One of the largest studies on facial pain was conducted using Biobank data. Cryopreservation of dental pulp stem cells is a common practice in tooth biobanks. With the exception of teeth and pulp, also leftover oral soft and hard tissues may represent a source of healthy samples that has rarely been exploited as yet. While biobanks are increasingly attracting the attention of the scientific community and becoming economically sustainable, a systematic approach to this resource in dentistry seems to be lacking. This review illustrates the applications of biobanking in dentistry, describing biobanked pathological and healthy samples and data, and discussing future developments. |
| first_indexed | 2024-04-11T05:12:12Z |
| format | Article |
| id | doaj.art-b6bf34a3953b440ab41f305be8444f93 |
| institution | Directory Open Access Journal |
| issn | 1882-7616 |
| language | English |
| last_indexed | 2024-04-11T05:12:12Z |
| publishDate | 2022-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Japanese Dental Science Review |
| spelling | doaj.art-b6bf34a3953b440ab41f305be8444f932022-12-25T04:17:15ZengElsevierJapanese Dental Science Review1882-76162022-11-01583140Biobanking in dentistry: A reviewStefano Sivolella0Anna Scanu1Zijing Xie2Sara Vianello3Edoardo Stellini4Department of Neuroscience, Dentistry Section, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyDepartment of Neuroscience, Dentistry Section, University of Padova, Via Giustiniani 2, 35128 Padova, Italy; Corresponding author.Department of Neuroscience, Dentistry Section, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyDepartment of Neuroscience, Neuromuscular Center, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyDepartment of Neuroscience, Dentistry Section, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyBiobanks are not-for-profit services for the collection, processing, storage and distribution of biological samples and data for research and diagnostic purposes. In dentistry, biological materials and data obtained from questionnaires investigating oral conditions can be stored and used for large-scale studies on oral and systemic diseases. To give some examples: gene expression microarrays obtained on biobanked specimens were used in the identification of genetic alterations in oral cancer; efforts to identify genetic mechanisms behind dental caries have been based on an integrative analysis of transcriptome-wide associations and messenger RNA expression. One of the largest studies on facial pain was conducted using Biobank data. Cryopreservation of dental pulp stem cells is a common practice in tooth biobanks. With the exception of teeth and pulp, also leftover oral soft and hard tissues may represent a source of healthy samples that has rarely been exploited as yet. While biobanks are increasingly attracting the attention of the scientific community and becoming economically sustainable, a systematic approach to this resource in dentistry seems to be lacking. This review illustrates the applications of biobanking in dentistry, describing biobanked pathological and healthy samples and data, and discussing future developments.http://www.sciencedirect.com/science/article/pii/S1882761621000454BiobankDentistryDental pulp stem cellsOral cancerGeneticsOral-systemic disease(s) |
| spellingShingle | Stefano Sivolella Anna Scanu Zijing Xie Sara Vianello Edoardo Stellini Biobanking in dentistry: A review Japanese Dental Science Review Biobank Dentistry Dental pulp stem cells Oral cancer Genetics Oral-systemic disease(s) |
| title | Biobanking in dentistry: A review |
| title_full | Biobanking in dentistry: A review |
| title_fullStr | Biobanking in dentistry: A review |
| title_full_unstemmed | Biobanking in dentistry: A review |
| title_short | Biobanking in dentistry: A review |
| title_sort | biobanking in dentistry a review |
| topic | Biobank Dentistry Dental pulp stem cells Oral cancer Genetics Oral-systemic disease(s) |
| url | http://www.sciencedirect.com/science/article/pii/S1882761621000454 |
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