Preclinical Assessment Addressing Intravenous Administration of a [<sup>68</sup>Ga]Ga-PSMA-617 Microemulsion: Acute In Vivo Toxicity, Tolerability, PET Imaging, and Biodistribution

Preclinical Assessment Addressing Intravenous Administration of a [<sup>68</sup>Ga]Ga-PSMA-617 Microemulsion: Acute In Vivo Toxicity, Tolerability, PET Imaging, and Biodistribution

It has been herein presented that a microemulsion, known to be an effective and safe drug delivery system following intravenous administration, can be loaded with traces of [<sup>68</sup>Ga]Ga-PSMA-617 without losing its properties or causing toxicity. Following tolerated IV injections t...

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Bibliographic Details
Main Authors: Vusani Mandiwana, Lonji Kalombo, Rose Hayeshi, Jan Rijn Zeevaart, Thomas Ebenhan
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
biodistribution
<sup>68</sup>Ga
[<sup>68</sup>Ga]Ga-PSMA-617-ME
in vivo
microemulsion
microPET/CT
Online Access:https://www.mdpi.com/1420-3049/26/9/2650

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