Epitope mapping and characterization of a novel Nsp10-specific monoclonal antibody that differentiates genotype 2 PRRSV from genotype 1 PRRSV

Epitope mapping and characterization of a novel Nsp10-specific monoclonal antibody that differentiates genotype 2 PRRSV from genotype 1 PRRSV

Abstract Background Porcine reproductive and respiratory syndrome virus (PRRSV), the causative agent of PRRS, has two distinct and highly diverse genotypes (genotype 1 and genotype 2) in the field. Accurate diagnosis and differentiation of the two genotypes of PRRSV are critical to the effective pre...

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Bibliographic Details
Main Authors: Zhibang Zhang, Xuexia Wen, Jianguo Dong, Xinna Ge, Lei Zhou, Hanchun Yang, Xin Guo
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Virology Journal
Subjects:
Porcine reproductive and respiratory syndrome virus (PRRSV)
Non-structural protein 10 (Nsp10)
Monoclonal antibody (mAb)
B-cell epitope
Differential diagnosis
Online Access:http://link.springer.com/article/10.1186/s12985-017-0782-9

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