Development and Optimization of Novel Emulgel Loaded with Andrographolide-Rich Extract and Sesame Oil Using Quality by Design Approach: In Silico and In Vitro Cytotoxic Evaluation against A431 Cells

Development and Optimization of Novel Emulgel Loaded with Andrographolide-Rich Extract and Sesame Oil Using Quality by Design Approach: In Silico and In Vitro Cytotoxic Evaluation against A431 Cells

An epidermoid carcinoma is a form of non-melanoma skin cancer that originates from the outer layer of the skin’s squamous cells. Previous studies have shown that andrographis extract and andrographolide inhibit the growth and proliferation of epidermoid carcinoma cells while also inducing cell cycle...

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Bibliographic Details
Main Authors: N. V. L. Sirisha Mulukuri, Moumita Dhara, Dheeraj Gupta, Kusum Devi, Pankaj Kumar
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Gels
Subjects:
<i>Andrographis paniculata</i>
anticancer
emulgels
non-melanoma
topical
Online Access:https://www.mdpi.com/2310-2861/9/7/507

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