The Cytoplasmic Region of SARAF Reduces Triple-Negative Breast Cancer Metastasis through the Regulation of Store-Operated Calcium Entry

The Cytoplasmic Region of SARAF Reduces Triple-Negative Breast Cancer Metastasis through the Regulation of Store-Operated Calcium Entry

Triple-negative breast cancer has a poor prognosis and is non-responsive to first-line therapies; hence, new therapeutic strategies are needed. Enhanced store-operated Ca<sup>2+</sup> entry (SOCE) has been widely described as a contributing factor to tumorigenic behavior in several tumor...

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Bibliographic Details
Main Authors: María Paz Saldías, Pablo Cruz, Ian Silva, Octavio Orellana-Serradell, Boris Lavanderos, Diego Maureira, Raquel Pinto, Oscar Cerda
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
triple-negative breast cancer
store-operated calcium entry
SARAF
cell migration
cell invasion
metastasis
Online Access:https://www.mdpi.com/1422-0067/24/6/5306

Internet

https://www.mdpi.com/1422-0067/24/6/5306

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