Development of an efficient and precise adenine base editor (ABE) with expanded target range in allotetraploid cotton (Gossypium hirsutum)

Development of an efficient and precise adenine base editor (ABE) with expanded target range in allotetraploid cotton (Gossypium hirsutum)

Abstract Background Base editors (BEs) display diverse applications in a variety of plant species such as Arabidopsis, rice, wheat, maize, soybean, and cotton, where they have been used to mediate precise base pair conversions without the collateral generation of undesirable double-stranded breaks (...

Full description

Bibliographic Details
Main Authors: Guanying Wang, Zhongping Xu, Fuqiu Wang, Yuefan Huang, Yanfeng Xin, Sijia Liang, Bo Li, Huan Si, Lin Sun, Qiongqiong Wang, Xiao Ding, Xiangqian Zhu, Luo Chen, Lu Yu, Keith Lindsey, Xianlong Zhang, Shuangxia Jin
Format: Article
Language:English
Published: BMC 2022-02-01
Series:BMC Biology
Subjects:
Cotton
CRISPR/nCas9
dCas9
dCpf1
Adenine base editors (ABEs)
Off-target mutations
Online Access:https://doi.org/10.1186/s12915-022-01232-3

Internet

https://doi.org/10.1186/s12915-022-01232-3

Similar Items