Bone marrow concentrate-induced mesenchymal stem cell conditioned medium facilitates wound healing and prevents hypertrophic scar formation in a rabbit ear model

Bone marrow concentrate-induced mesenchymal stem cell conditioned medium facilitates wound healing and prevents hypertrophic scar formation in a rabbit ear model

Abstract Background Hypertrophic scars (HSs) are formed via an aberrant response to the wound healing process. HSs can be cosmetic or can result in functional problems. Prolonged proliferation and remodeling phases disrupt wound healing, leading to excessive collagen production and HS formation. How...

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Bibliographic Details
Main Authors: Ching-Hsuan Hu, Yi-Wen Tseng, Chih-Yung Chiou, Kuan-Chun Lan, Chih-Hung Chou, Chun-San Tai, Hsien-Da Huang, Chiung-Wen Hu, Ko-Hsun Liao, Shiow-Shuh Chuang, Jui-Yung Yang, Oscar K. Lee
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Stem Cell Research & Therapy
Subjects:
Hypertrophic scar
Bone marrow concentrate
Mesenchymal stem cell-conditioned medium
Online Access:http://link.springer.com/article/10.1186/s13287-019-1383-x

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