Gastrointestinal cancers, ACE-2/TMPRSS2 expression and susceptibility to COVID-19

Gastrointestinal cancers, ACE-2/TMPRSS2 expression and susceptibility to COVID-19

Abstract Recent studies on the pathophysiology of COVID-19 are indicating that the Angiotensin convertase enzyme 2 (ACE-2) and transmembrane serine protease 2 (TMPRSS2) can act as a major component in the fusion of SARS-Cov-2 with target cells. It has also been observed that the expression of ACE-2...

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Main Authors: Sepehr Shafiee, Luca Cegolon, Mostafa Khafaei, Nasrin Gholami, Shi Zhao, Nasrin Khalesi, Hamidreza Moosavian, Saeid Fathi, Morteza Izadi, Alireza Ghadian, Mohammad Javanbakht, Amin Javanbakht, Reza Akhavan-Sigari
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Cancer Cell International
Subjects:
Gastrointestinal cancer
COVID-19
Angiotensin convertase enzyme 2
transmembrane serine protease 2
Pathophysiology
Online Access:https://doi.org/10.1186/s12935-021-02129-x

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