Identification of Molecular Basis for Objective Discrimination of Breast Cancer Cells (MCF-7) from Normal Human Mammary Epithelial Cells by Raman Microspectroscopy and Multivariate Curve Resolution Analysis

Identification of Molecular Basis for Objective Discrimination of Breast Cancer Cells (MCF-7) from Normal Human Mammary Epithelial Cells by Raman Microspectroscopy and Multivariate Curve Resolution Analysis

Raman spectroscopy (RS), a non-invasive and label-free method, has been suggested to improve accuracy of cytological and even histopathological diagnosis. To our knowledge, this novel technique tends to be employed without concrete knowledge of molecular changes in cells. Therefore, identification o...

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Bibliographic Details
Main Authors: Keita Iwasaki, Asuka Araki, C Murali Krishna, Riruke Maruyama, Tatsuyuki Yamamoto, Hemanth Noothalapati
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
Raman spectroscopy
breast cancer
linoleic acid
lipid metabolism
PUFA
cancer diagnosis
Online Access:https://www.mdpi.com/1422-0067/22/2/800

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