ISOLATION AND STRUCTURE ELUCIDATION OF SECONDARY METABOLITE COMPOUNDS FROM Curcuma aeruginosa
Black turmeric (Curcuma aeruginosa) is Indonesian medicinal plant belonging to the Zingeberaceae family, mostly found on Java. This study aimed to determine the new molecular structures of the compounds isolated from black turmeric originating from Indonesia. Isolation of the secondary metabolite co...
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| Format: | Article |
| Language: | English |
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Universitas Airlangga
2023-06-01
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| Series: | Jurnal Kimia Riset |
| Subjects: | |
| Online Access: | https://e-journal.unair.ac.id/JKR/article/view/44073 |
| _version_ | 1797788548609343488 |
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| author | Alsya Firdausi Nuzula Alfinda Novi Kristanti Nanik Siti Aminah Yoshiaki Takaya Marisa Nur Sahadatin Andika Pramudya Wardana |
| author_facet | Alsya Firdausi Nuzula Alfinda Novi Kristanti Nanik Siti Aminah Yoshiaki Takaya Marisa Nur Sahadatin Andika Pramudya Wardana |
| author_sort | Alsya Firdausi Nuzula |
| collection | DOAJ |
| description | Black turmeric (Curcuma aeruginosa) is Indonesian medicinal plant belonging to the Zingeberaceae family, mostly found on Java. This study aimed to determine the new molecular structures of the compounds isolated from black turmeric originating from Indonesia. Isolation of the secondary metabolite compounds was initiated by solid-liquid extraction using the maceration method with ethanol solvent, followed by liquid-liquid extraction using the partition method with n-hexane and dichloromethane as solvents. Separation and purification were carried out using vacuum liquid chromatography (VLC) and gravity column chromatography (GCC). The isolated compounds were characterized using spectroscopic methods, including UV-Vis, IR, and NMR spectroscopy. The isolation resulted in three sesquiterpenoid compounds, (E)-7-isopropyl-4,10-dimethylcyclodec-10-ene-5,8-dione (curdione), (1R,10R)-Epoxy-(-)-1,10-dihydrocurdione, and zedoalactone B, together with two common terpenes, ethyl tetradecanoate and 1-hexadecene. |
| first_indexed | 2024-03-13T01:37:11Z |
| format | Article |
| id | doaj.art-b6d9b907d50641499fc4e4a99b8897d8 |
| institution | Directory Open Access Journal |
| issn | 2528-0414 2528-0422 |
| language | English |
| last_indexed | 2024-03-13T01:37:11Z |
| publishDate | 2023-06-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Jurnal Kimia Riset |
| spelling | doaj.art-b6d9b907d50641499fc4e4a99b8897d82023-07-04T02:26:30ZengUniversitas AirlanggaJurnal Kimia Riset2528-04142528-04222023-06-0181819110.20473/jkr.v8i1.4407342155ISOLATION AND STRUCTURE ELUCIDATION OF SECONDARY METABOLITE COMPOUNDS FROM Curcuma aeruginosaAlsya Firdausi Nuzula0Alfinda Novi Kristanti1Nanik Siti Aminah2Yoshiaki Takaya3Marisa Nur Sahadatin4Andika Pramudya Wardana5Universitas AirlanggaDepartment of Chemistry, Faculty of Science and Technology Universitas Airlangga, SurabayaUniversitas AirlanggaMeijo UniversityUniversitas AirlanggaUniversitas AirlanggaBlack turmeric (Curcuma aeruginosa) is Indonesian medicinal plant belonging to the Zingeberaceae family, mostly found on Java. This study aimed to determine the new molecular structures of the compounds isolated from black turmeric originating from Indonesia. Isolation of the secondary metabolite compounds was initiated by solid-liquid extraction using the maceration method with ethanol solvent, followed by liquid-liquid extraction using the partition method with n-hexane and dichloromethane as solvents. Separation and purification were carried out using vacuum liquid chromatography (VLC) and gravity column chromatography (GCC). The isolated compounds were characterized using spectroscopic methods, including UV-Vis, IR, and NMR spectroscopy. The isolation resulted in three sesquiterpenoid compounds, (E)-7-isopropyl-4,10-dimethylcyclodec-10-ene-5,8-dione (curdione), (1R,10R)-Epoxy-(-)-1,10-dihydrocurdione, and zedoalactone B, together with two common terpenes, ethyl tetradecanoate and 1-hexadecene.https://e-journal.unair.ac.id/JKR/article/view/44073black turmericcurcuma aeruginosamedicinal plantsesquiterpenoidszingiberaceae |
| spellingShingle | Alsya Firdausi Nuzula Alfinda Novi Kristanti Nanik Siti Aminah Yoshiaki Takaya Marisa Nur Sahadatin Andika Pramudya Wardana ISOLATION AND STRUCTURE ELUCIDATION OF SECONDARY METABOLITE COMPOUNDS FROM Curcuma aeruginosa Jurnal Kimia Riset black turmeric curcuma aeruginosa medicinal plant sesquiterpenoids zingiberaceae |
| title | ISOLATION AND STRUCTURE ELUCIDATION OF SECONDARY METABOLITE COMPOUNDS FROM Curcuma aeruginosa |
| title_full | ISOLATION AND STRUCTURE ELUCIDATION OF SECONDARY METABOLITE COMPOUNDS FROM Curcuma aeruginosa |
| title_fullStr | ISOLATION AND STRUCTURE ELUCIDATION OF SECONDARY METABOLITE COMPOUNDS FROM Curcuma aeruginosa |
| title_full_unstemmed | ISOLATION AND STRUCTURE ELUCIDATION OF SECONDARY METABOLITE COMPOUNDS FROM Curcuma aeruginosa |
| title_short | ISOLATION AND STRUCTURE ELUCIDATION OF SECONDARY METABOLITE COMPOUNDS FROM Curcuma aeruginosa |
| title_sort | isolation and structure elucidation of secondary metabolite compounds from curcuma aeruginosa |
| topic | black turmeric curcuma aeruginosa medicinal plant sesquiterpenoids zingiberaceae |
| url | https://e-journal.unair.ac.id/JKR/article/view/44073 |
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