In Vitro Effects of Fungal Phytotoxins on Cancer Cell Viability: First Insight into Structure Activity Relationship of a Potent Metabolite of <i>Cochliobolus australiensis</i> Radicinin

In Vitro Effects of Fungal Phytotoxins on Cancer Cell Viability: First Insight into Structure Activity Relationship of a Potent Metabolite of <i>Cochliobolus australiensis</i> Radicinin

Natural compounds have always represented an important source for new drugs. Although fungi represent one such viable source, to date, no fungal metabolite has been marketed as an anticancer drug. Based on our work with phytotoxins as potential chemical scaffolds and our recent findings involving th...

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Bibliographic Details
Main Authors: Veronique Mathieu, Stefano Superchi, Marco Masi, Patrizia Scafato, Alexander Kornienko, Antonio Evidente
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Toxins
Subjects:
fungi
phytotoxins
radicinin
natural and hemisynthetic derivatives
anticancer
SAR study
Online Access:https://www.mdpi.com/2072-6651/14/8/517

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