CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL
Covid-19 caused by the SARS-CoV-2 virus and is transmitted through droplets. In Covid-19 patients who are critical or have severe symptoms, hypercytokines are often found, which is characterized by an increase in the cytokine Interleukin-6 (IL-6). High levels of IL-6 cytokines can disrupt the immun...
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Format: | Article |
Language: | Indonesian |
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Fakultas Kesehatan Universitas Nahdlatul Ulama Surabaya
2022-10-01
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Series: | Medical Technology and Public Health Journal |
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Online Access: | https://journal2.unusa.ac.id/index.php/MTPHJ/article/view/2768 |
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author | Mimah Mulhimah Dian Rachma Wijayanti Frida Octavia Purnomo |
author_facet | Mimah Mulhimah Dian Rachma Wijayanti Frida Octavia Purnomo |
author_sort | Mimah Mulhimah |
collection | DOAJ |
description |
Covid-19 caused by the SARS-CoV-2 virus and is transmitted through droplets. In Covid-19 patients who are critical or have severe symptoms, hypercytokines are often found, which is characterized by an increase in the cytokine Interleukin-6 (IL-6). High levels of IL-6 cytokines can disrupt the immune system, including leukocytes, especially lymphocytes, which are the main system of the immune response. The state of continued inflammation and continuously stimulated lymphocytes will cause the lymphocytes to work too hard. This study aims to determine the relationship of Interleukin-6 (IL-6) with lymphocytes in Covid-19 positive patients. This study is a quantitative research with correlation analysis method using data collection technique by purposive sampling. Furthermore, to analyze, the authors used the Kolmogorov-Smirnov normality test and the Spearman correlation test. The results of the analysis showed a fairly significant correlation between levels of Interleukin-6 (IL-6) and the number of lymphocytes in Covid-19 positive patients.
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first_indexed | 2024-04-11T07:54:04Z |
format | Article |
id | doaj.art-b6dcd7ad4da4411ca6bc2f36e8c1afc7 |
institution | Directory Open Access Journal |
issn | 2549-189X 2549-2993 |
language | Indonesian |
last_indexed | 2024-04-11T07:54:04Z |
publishDate | 2022-10-01 |
publisher | Fakultas Kesehatan Universitas Nahdlatul Ulama Surabaya |
record_format | Article |
series | Medical Technology and Public Health Journal |
spelling | doaj.art-b6dcd7ad4da4411ca6bc2f36e8c1afc72022-12-22T04:35:59ZindFakultas Kesehatan Universitas Nahdlatul Ulama SurabayaMedical Technology and Public Health Journal2549-189X2549-29932022-10-016110.33086/mtphj.v6i1.2768CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITALMimah Mulhimah0Dian Rachma Wijayanti1Frida Octavia Purnomo2Binawan UniversityBinawan UniversityBinawan University Covid-19 caused by the SARS-CoV-2 virus and is transmitted through droplets. In Covid-19 patients who are critical or have severe symptoms, hypercytokines are often found, which is characterized by an increase in the cytokine Interleukin-6 (IL-6). High levels of IL-6 cytokines can disrupt the immune system, including leukocytes, especially lymphocytes, which are the main system of the immune response. The state of continued inflammation and continuously stimulated lymphocytes will cause the lymphocytes to work too hard. This study aims to determine the relationship of Interleukin-6 (IL-6) with lymphocytes in Covid-19 positive patients. This study is a quantitative research with correlation analysis method using data collection technique by purposive sampling. Furthermore, to analyze, the authors used the Kolmogorov-Smirnov normality test and the Spearman correlation test. The results of the analysis showed a fairly significant correlation between levels of Interleukin-6 (IL-6) and the number of lymphocytes in Covid-19 positive patients. https://journal2.unusa.ac.id/index.php/MTPHJ/article/view/2768Covid-19, Interleukin-6, Hypercytokine |
spellingShingle | Mimah Mulhimah Dian Rachma Wijayanti Frida Octavia Purnomo CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL Medical Technology and Public Health Journal Covid-19, Interleukin-6, Hypercytokine |
title | CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL |
title_full | CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL |
title_fullStr | CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL |
title_full_unstemmed | CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL |
title_short | CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL |
title_sort | correlation of interleukin 6 il 6 level and number of lymphocytes in covid 19 positive patients at persahabatan hospital |
topic | Covid-19, Interleukin-6, Hypercytokine |
url | https://journal2.unusa.ac.id/index.php/MTPHJ/article/view/2768 |
work_keys_str_mv | AT mimahmulhimah correlationofinterleukin6il6levelandnumberoflymphocytesincovid19positivepatientsatpersahabatanhospital AT dianrachmawijayanti correlationofinterleukin6il6levelandnumberoflymphocytesincovid19positivepatientsatpersahabatanhospital AT fridaoctaviapurnomo correlationofinterleukin6il6levelandnumberoflymphocytesincovid19positivepatientsatpersahabatanhospital |