CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL

Covid-19 caused by the SARS-CoV-2 virus and is transmitted through droplets. In Covid-19 patients who are critical or have severe symptoms, hypercytokines are often found, which is characterized by an increase in the cytokine Interleukin-6 (IL-6). High levels of IL-6 cytokines can disrupt the immun...

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Main Authors: Mimah Mulhimah, Dian Rachma Wijayanti, Frida Octavia Purnomo
Format: Article
Language:Indonesian
Published: Fakultas Kesehatan Universitas Nahdlatul Ulama Surabaya 2022-10-01
Series:Medical Technology and Public Health Journal
Subjects:
Online Access:https://journal2.unusa.ac.id/index.php/MTPHJ/article/view/2768
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author Mimah Mulhimah
Dian Rachma Wijayanti
Frida Octavia Purnomo
author_facet Mimah Mulhimah
Dian Rachma Wijayanti
Frida Octavia Purnomo
author_sort Mimah Mulhimah
collection DOAJ
description Covid-19 caused by the SARS-CoV-2 virus and is transmitted through droplets. In Covid-19 patients who are critical or have severe symptoms, hypercytokines are often found, which is characterized by an increase in the cytokine Interleukin-6 (IL-6). High levels of IL-6 cytokines can disrupt the immune system, including leukocytes, especially lymphocytes, which are the main system of the immune response. The state of continued inflammation and continuously stimulated lymphocytes will cause the lymphocytes to work too hard. This study aims to determine the relationship of Interleukin-6 (IL-6) with lymphocytes in Covid-19 positive patients. This study is a quantitative research with correlation analysis method using data collection technique by purposive sampling. Furthermore, to analyze, the authors used the Kolmogorov-Smirnov normality test and the Spearman correlation test. The results of the analysis showed a fairly significant correlation between levels of Interleukin-6 (IL-6) and the number of lymphocytes in Covid-19 positive patients.
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spelling doaj.art-b6dcd7ad4da4411ca6bc2f36e8c1afc72022-12-22T04:35:59ZindFakultas Kesehatan Universitas Nahdlatul Ulama SurabayaMedical Technology and Public Health Journal2549-189X2549-29932022-10-016110.33086/mtphj.v6i1.2768CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITALMimah Mulhimah0Dian Rachma Wijayanti1Frida Octavia Purnomo2Binawan UniversityBinawan UniversityBinawan University Covid-19 caused by the SARS-CoV-2 virus and is transmitted through droplets. In Covid-19 patients who are critical or have severe symptoms, hypercytokines are often found, which is characterized by an increase in the cytokine Interleukin-6 (IL-6). High levels of IL-6 cytokines can disrupt the immune system, including leukocytes, especially lymphocytes, which are the main system of the immune response. The state of continued inflammation and continuously stimulated lymphocytes will cause the lymphocytes to work too hard. This study aims to determine the relationship of Interleukin-6 (IL-6) with lymphocytes in Covid-19 positive patients. This study is a quantitative research with correlation analysis method using data collection technique by purposive sampling. Furthermore, to analyze, the authors used the Kolmogorov-Smirnov normality test and the Spearman correlation test. The results of the analysis showed a fairly significant correlation between levels of Interleukin-6 (IL-6) and the number of lymphocytes in Covid-19 positive patients. https://journal2.unusa.ac.id/index.php/MTPHJ/article/view/2768Covid-19, Interleukin-6, Hypercytokine
spellingShingle Mimah Mulhimah
Dian Rachma Wijayanti
Frida Octavia Purnomo
CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL
Medical Technology and Public Health Journal
Covid-19, Interleukin-6, Hypercytokine
title CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL
title_full CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL
title_fullStr CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL
title_full_unstemmed CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL
title_short CORRELATION OF INTERLEUKIN-6 (IL-6) LEVEL AND NUMBER OF LYMPHOCYTES IN COVID-19 POSITIVE PATIENTS AT PERSAHABATAN HOSPITAL
title_sort correlation of interleukin 6 il 6 level and number of lymphocytes in covid 19 positive patients at persahabatan hospital
topic Covid-19, Interleukin-6, Hypercytokine
url https://journal2.unusa.ac.id/index.php/MTPHJ/article/view/2768
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AT fridaoctaviapurnomo correlationofinterleukin6il6levelandnumberoflymphocytesincovid19positivepatientsatpersahabatanhospital