Molecular characterization of rpoB gene mutations in isolates from tuberculosis patients in Cubal, Republic of Angola

Molecular characterization of rpoB gene mutations in isolates from tuberculosis patients in Cubal, Republic of Angola

Abstract Background The importance of Mycobacterium tuberculosis strains with disputed rpoB mutations remains to be defined. This study aimed to assess the frequency and types of rpoB mutations in M. tuberculosis isolates from Cubal, Angola, a country with a high incidence of tuberculosis. Methods A...

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Bibliographic Details
Main Authors: Ariadna Rando-Segura, María Luisa Aznar, María Milagros Moreno, Mateu Espasa Soley, Elena Sulleiro Igual, Cristina Bocanegra Garcia, Eva Gil Olivas, Arlete Nindia Eugénio, Carlos Escartin Huesca, Adriano Zacarias, Josep Vegue Collado, Domingos Katimba, Maria Carmen Vivas Cano, Estevao Gabriel, Maria Teresa López García, Tomas Pumarola Suñe, Israel Molina Romero, María Teresa Tórtola Fernández
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Infectious Diseases
Subjects:
Angola
Cubal
GenoType MTBDRplus VER2.0
Resistance
Rifampicin
rpoB mutations
Online Access:https://doi.org/10.1186/s12879-021-06763-8

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