Supraventricular tachyarrhythmia in patients with Brugada syndrome: A single-center study
Background: Brugada syndrome is a distinct form of idiopathic ventricular fibrillation. We retrospectively investigated the incidence and clinical implications of supraventricular tachyarrhythmia in patients with Brugada syndrome. Methods: We reviewed 69 consecutive cases of Brugada syndrome, 11 of...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-10-01
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| Series: | Journal of Arrhythmia |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1880427613000483 |
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| author | Kimie Ohkubo Ichiro Watanabe Yasuo Okumura Masayoshi Kofune Koichi Nagashima Hiroaki Mano Kazumasa Sonoda Toshiko Nakai Satoshi Kunimoto Yuji Kasamaki Atsushi Hirayama Naokata Sumitomo Tomohiro Nakayama |
| author_facet | Kimie Ohkubo Ichiro Watanabe Yasuo Okumura Masayoshi Kofune Koichi Nagashima Hiroaki Mano Kazumasa Sonoda Toshiko Nakai Satoshi Kunimoto Yuji Kasamaki Atsushi Hirayama Naokata Sumitomo Tomohiro Nakayama |
| author_sort | Kimie Ohkubo |
| collection | DOAJ |
| description | Background: Brugada syndrome is a distinct form of idiopathic ventricular fibrillation. We retrospectively investigated the incidence and clinical implications of supraventricular tachyarrhythmia in patients with Brugada syndrome.
Methods: We reviewed 69 consecutive cases of Brugada syndrome, 11 of which had a history of syncope.
Results: Seven patients (10.1%) had clinically documented supraventricular tachyarrhythmia: 3 patients with atrioventricular reentrant tachycardia, 2 with atrioventricular nodal reentrant tachycardia, and 2 with paroxysmal atrial fibrillation. The prevalence of a spontaneous type 1 Brugada electrocardiogram and symptoms (history of syncope, presyncope, documented ventricular tachyarrhythmia, or aborted sudden cardiac death) were significantly higher, and QRS duration was significantly longer in patients without than in those with supraventricular tachyarrhythmia. The PR and AH intervals were also longer in patients without than in those with supraventricular tachyarrhythmia, but the differences were not statistically significant.
Conclusion: The arrhythmogenic substrate in Brugada syndrome may not be restricted to the ventricles. Palpitations in patients with this syndrome should raise the question of supraventricular tachyarrhythmia. Conversely, in patients with supraventricular tachyarrhythmia and aborted sudden cardiac death or syncope not related to supraventricular tachyarrhythmia, Brugada syndrome should be considered a possible additional electrophysiologic abnormality. |
| first_indexed | 2024-12-12T20:30:18Z |
| format | Article |
| id | doaj.art-b6e6088f5f78408ca771f6ec81763bd7 |
| institution | Directory Open Access Journal |
| issn | 1880-4276 |
| language | English |
| last_indexed | 2024-12-12T20:30:18Z |
| publishDate | 2013-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Arrhythmia |
| spelling | doaj.art-b6e6088f5f78408ca771f6ec81763bd72022-12-22T00:13:03ZengWileyJournal of Arrhythmia1880-42762013-10-0129526526910.1016/j.joa.2013.01.014Supraventricular tachyarrhythmia in patients with Brugada syndrome: A single-center studyKimie Ohkubo0Ichiro Watanabe1Yasuo Okumura2Masayoshi Kofune3Koichi Nagashima4Hiroaki Mano5Kazumasa Sonoda6Toshiko Nakai7Satoshi Kunimoto8Yuji Kasamaki9Atsushi Hirayama10Naokata Sumitomo11Tomohiro Nakayama12Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, JapanDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, JapanDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, JapanDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, JapanDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, JapanDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, JapanDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, JapanDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, JapanDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, JapanDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, JapanDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, JapanDepartment of Pediatrics, Nihon University School of Medicine, Tokyo, JapanDepartment of Laboratory Medicine, Nihon University School of Medicine, Tokyo, JapanBackground: Brugada syndrome is a distinct form of idiopathic ventricular fibrillation. We retrospectively investigated the incidence and clinical implications of supraventricular tachyarrhythmia in patients with Brugada syndrome. Methods: We reviewed 69 consecutive cases of Brugada syndrome, 11 of which had a history of syncope. Results: Seven patients (10.1%) had clinically documented supraventricular tachyarrhythmia: 3 patients with atrioventricular reentrant tachycardia, 2 with atrioventricular nodal reentrant tachycardia, and 2 with paroxysmal atrial fibrillation. The prevalence of a spontaneous type 1 Brugada electrocardiogram and symptoms (history of syncope, presyncope, documented ventricular tachyarrhythmia, or aborted sudden cardiac death) were significantly higher, and QRS duration was significantly longer in patients without than in those with supraventricular tachyarrhythmia. The PR and AH intervals were also longer in patients without than in those with supraventricular tachyarrhythmia, but the differences were not statistically significant. Conclusion: The arrhythmogenic substrate in Brugada syndrome may not be restricted to the ventricles. Palpitations in patients with this syndrome should raise the question of supraventricular tachyarrhythmia. Conversely, in patients with supraventricular tachyarrhythmia and aborted sudden cardiac death or syncope not related to supraventricular tachyarrhythmia, Brugada syndrome should be considered a possible additional electrophysiologic abnormality.http://www.sciencedirect.com/science/article/pii/S1880427613000483Brugada syndromeSupraventricular tachycardiaAtrial fibrillation |
| spellingShingle | Kimie Ohkubo Ichiro Watanabe Yasuo Okumura Masayoshi Kofune Koichi Nagashima Hiroaki Mano Kazumasa Sonoda Toshiko Nakai Satoshi Kunimoto Yuji Kasamaki Atsushi Hirayama Naokata Sumitomo Tomohiro Nakayama Supraventricular tachyarrhythmia in patients with Brugada syndrome: A single-center study Journal of Arrhythmia Brugada syndrome Supraventricular tachycardia Atrial fibrillation |
| title | Supraventricular tachyarrhythmia in patients with Brugada syndrome: A single-center study |
| title_full | Supraventricular tachyarrhythmia in patients with Brugada syndrome: A single-center study |
| title_fullStr | Supraventricular tachyarrhythmia in patients with Brugada syndrome: A single-center study |
| title_full_unstemmed | Supraventricular tachyarrhythmia in patients with Brugada syndrome: A single-center study |
| title_short | Supraventricular tachyarrhythmia in patients with Brugada syndrome: A single-center study |
| title_sort | supraventricular tachyarrhythmia in patients with brugada syndrome a single center study |
| topic | Brugada syndrome Supraventricular tachycardia Atrial fibrillation |
| url | http://www.sciencedirect.com/science/article/pii/S1880427613000483 |
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