EXPERIENCE OF OSMOTIC LAXATIVES (POLYETHYLENE GLYCOL 4000) USAGE IN TREATMENT OF CHRONIC CONSTIPATION IN CHILDREN

Aim: to assess clinical efficacy of polietilenglicol (macrogol) with molecular weight 4000 kDa in children with chronic constipation. Patients and methods: clinical efficacy was assessed in 30 children aged 2–12 years with chronic constipation. The follow-up was performed on an out-patient basis, pa...

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Main Author: A. V. Eremeeva
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2013-07-01
Series:Вопросы современной педиатрии
Subjects:
Online Access:https://vsp.spr-journal.ru/jour/article/view/321
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author A. V. Eremeeva
author_facet A. V. Eremeeva
author_sort A. V. Eremeeva
collection DOAJ
description Aim: to assess clinical efficacy of polietilenglicol (macrogol) with molecular weight 4000 kDa in children with chronic constipation. Patients and methods: clinical efficacy was assessed in 30 children aged 2–12 years with chronic constipation. The follow-up was performed on an out-patient basis, patients and their parents kept diaries, noting stool characteristics according to the Bristol stool scale. Coprological analysis and abdominal ultrasound were carried out. The duration of the follow-up after the withdrawal of the studied drug was 6 months. Results: during the 1st week of treatment the frequency of stool increased in 23 (76,6%) children, normalization of stool frequency to the 4th week of treatment was achieved in 93,3% of patients. Stool consistency in 1 month of treatment met criteria of the 3d and 4th types according to the Bristol stool scale in 27 (90%) children. Painful defecations have been arrested by the 3d week of treatment. Conclusions: the drug was shown to be highly effective in treatment of chronic constipation in children, arresting such symptoms as «fear of the potty» and painful defecations and having a strong positive dynamics after its withdrawal.
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spelling doaj.art-b6ed644a6fa54407b226af9ae302d8ed2025-03-02T11:34:06Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352013-07-0112417217510.15690/vsp.v12i4.747321EXPERIENCE OF OSMOTIC LAXATIVES (POLYETHYLENE GLYCOL 4000) USAGE IN TREATMENT OF CHRONIC CONSTIPATION IN CHILDRENA. V. Eremeeva0I.M. Sechenov First Moscow State Medical University,Aim: to assess clinical efficacy of polietilenglicol (macrogol) with molecular weight 4000 kDa in children with chronic constipation. Patients and methods: clinical efficacy was assessed in 30 children aged 2–12 years with chronic constipation. The follow-up was performed on an out-patient basis, patients and their parents kept diaries, noting stool characteristics according to the Bristol stool scale. Coprological analysis and abdominal ultrasound were carried out. The duration of the follow-up after the withdrawal of the studied drug was 6 months. Results: during the 1st week of treatment the frequency of stool increased in 23 (76,6%) children, normalization of stool frequency to the 4th week of treatment was achieved in 93,3% of patients. Stool consistency in 1 month of treatment met criteria of the 3d and 4th types according to the Bristol stool scale in 27 (90%) children. Painful defecations have been arrested by the 3d week of treatment. Conclusions: the drug was shown to be highly effective in treatment of chronic constipation in children, arresting such symptoms as «fear of the potty» and painful defecations and having a strong positive dynamics after its withdrawal.https://vsp.spr-journal.ru/jour/article/view/321children, chronic constipation, osmotic laxative
spellingShingle A. V. Eremeeva
EXPERIENCE OF OSMOTIC LAXATIVES (POLYETHYLENE GLYCOL 4000) USAGE IN TREATMENT OF CHRONIC CONSTIPATION IN CHILDREN
Вопросы современной педиатрии
children, chronic constipation, osmotic laxative
title EXPERIENCE OF OSMOTIC LAXATIVES (POLYETHYLENE GLYCOL 4000) USAGE IN TREATMENT OF CHRONIC CONSTIPATION IN CHILDREN
title_full EXPERIENCE OF OSMOTIC LAXATIVES (POLYETHYLENE GLYCOL 4000) USAGE IN TREATMENT OF CHRONIC CONSTIPATION IN CHILDREN
title_fullStr EXPERIENCE OF OSMOTIC LAXATIVES (POLYETHYLENE GLYCOL 4000) USAGE IN TREATMENT OF CHRONIC CONSTIPATION IN CHILDREN
title_full_unstemmed EXPERIENCE OF OSMOTIC LAXATIVES (POLYETHYLENE GLYCOL 4000) USAGE IN TREATMENT OF CHRONIC CONSTIPATION IN CHILDREN
title_short EXPERIENCE OF OSMOTIC LAXATIVES (POLYETHYLENE GLYCOL 4000) USAGE IN TREATMENT OF CHRONIC CONSTIPATION IN CHILDREN
title_sort experience of osmotic laxatives polyethylene glycol 4000 usage in treatment of chronic constipation in children
topic children, chronic constipation, osmotic laxative
url https://vsp.spr-journal.ru/jour/article/view/321
work_keys_str_mv AT averemeeva experienceofosmoticlaxativespolyethyleneglycol4000usageintreatmentofchronicconstipationinchildren