Risk Factors for Delirium after Spine Surgery: An Age-Matched Analysis
Study Design A retrospective cohort study. Purpose To investigate the risk factors for postoperative delirium after spine surgery, excluding older age, which has already been established as a strong risk factor. Overview of Literature More than 30 risk factors have been reported for delirium after s...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Spine Society
2018-08-01
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| Series: | Asian Spine Journal |
| Subjects: | |
| Online Access: | http://www.asianspinejournal.org/upload/pdf/asj-2018-12-4-703.pdf |
| _version_ | 1818527658648010752 |
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| author | Tadao Morino Masayuki Hino Shintaro Yamaoka Hiroshi Misaki Tadanori Ogata Hiroshi Imai Hiromasa Miura |
| author_facet | Tadao Morino Masayuki Hino Shintaro Yamaoka Hiroshi Misaki Tadanori Ogata Hiroshi Imai Hiromasa Miura |
| author_sort | Tadao Morino |
| collection | DOAJ |
| description | Study Design A retrospective cohort study. Purpose To investigate the risk factors for postoperative delirium after spine surgery, excluding older age, which has already been established as a strong risk factor. Overview of Literature More than 30 risk factors have been reported for delirium after spine surgery, making it challenging to identify which factors should be prioritized. We hypothesized that risk factors could not be prioritized to date because the factor of older age is very strong and influenced other factors. To eliminate the influence of older age, we performed an age-matched group comparison analysis for the investigation of other risk factors. Methods This study involved 532 patients who underwent spine surgery. Two patients of the same age without delirium (delirium negative group) were matched to each patient with delirium (delirium positive group). Differences in suspected risk factors for post-operative delirium between the two groups identified from previous reports were analyzed using univariate analysis. Multivariate analysis was performed for factors that showed a significant difference between the two groups in the univariate analysis. Results Fifty-nine (11.1%) of 532 patients developed postoperative delirium after spine surgery. Large amounts of intraoperative bleeding, low preoperative concentration of serum Na, high postoperative (day after surgery) serum level of C-reactive protein, low hematocrit level, low concentration of albumin, and high body temperature were detected as significant risk factors in the univariate analysis. Large amounts of intraoperative bleeding remained a risk factor for postoperative delirium in the multivariate analysis. Conclusions We should pay attention to and take precautions against the occurrence of postoperative delirium after spine surgery in patients of older age or those who experience severe intraoperative bleeding. |
| first_indexed | 2024-12-11T06:38:59Z |
| format | Article |
| id | doaj.art-b6f0246d31044d78b495d243e14aa82f |
| institution | Directory Open Access Journal |
| issn | 1976-1902 1976-7846 |
| language | English |
| last_indexed | 2024-12-11T06:38:59Z |
| publishDate | 2018-08-01 |
| publisher | Korean Spine Society |
| record_format | Article |
| series | Asian Spine Journal |
| spelling | doaj.art-b6f0246d31044d78b495d243e14aa82f2022-12-22T01:17:18ZengKorean Spine SocietyAsian Spine Journal1976-19021976-78462018-08-0112470370910.31616/asj.2018.12.4.703924Risk Factors for Delirium after Spine Surgery: An Age-Matched AnalysisTadao Morino0Masayuki Hino1Shintaro Yamaoka2Hiroshi Misaki3Tadanori Ogata4Hiroshi Imai5Hiromasa Miura6 Spine Center, Ehime University School of Medicine, Ehime, Japan Spine Center, Ehime University School of Medicine, Ehime, Japan Spine Center, Ehime University School of Medicine, Ehime, Japan Spine Center, Ehime University School of Medicine, Ehime, Japan Spine Center, Ehime University School of Medicine, Ehime, Japan Department of Orthopedic Surgery, Ehime University School of Medicine, Ehime, Japan Department of Orthopedic Surgery, Ehime University School of Medicine, Ehime, JapanStudy Design A retrospective cohort study. Purpose To investigate the risk factors for postoperative delirium after spine surgery, excluding older age, which has already been established as a strong risk factor. Overview of Literature More than 30 risk factors have been reported for delirium after spine surgery, making it challenging to identify which factors should be prioritized. We hypothesized that risk factors could not be prioritized to date because the factor of older age is very strong and influenced other factors. To eliminate the influence of older age, we performed an age-matched group comparison analysis for the investigation of other risk factors. Methods This study involved 532 patients who underwent spine surgery. Two patients of the same age without delirium (delirium negative group) were matched to each patient with delirium (delirium positive group). Differences in suspected risk factors for post-operative delirium between the two groups identified from previous reports were analyzed using univariate analysis. Multivariate analysis was performed for factors that showed a significant difference between the two groups in the univariate analysis. Results Fifty-nine (11.1%) of 532 patients developed postoperative delirium after spine surgery. Large amounts of intraoperative bleeding, low preoperative concentration of serum Na, high postoperative (day after surgery) serum level of C-reactive protein, low hematocrit level, low concentration of albumin, and high body temperature were detected as significant risk factors in the univariate analysis. Large amounts of intraoperative bleeding remained a risk factor for postoperative delirium in the multivariate analysis. Conclusions We should pay attention to and take precautions against the occurrence of postoperative delirium after spine surgery in patients of older age or those who experience severe intraoperative bleeding.http://www.asianspinejournal.org/upload/pdf/asj-2018-12-4-703.pdfSpineDeliriumRisk factorsMultivariate analysisHemorrhage |
| spellingShingle | Tadao Morino Masayuki Hino Shintaro Yamaoka Hiroshi Misaki Tadanori Ogata Hiroshi Imai Hiromasa Miura Risk Factors for Delirium after Spine Surgery: An Age-Matched Analysis Asian Spine Journal Spine Delirium Risk factors Multivariate analysis Hemorrhage |
| title | Risk Factors for Delirium after Spine Surgery: An Age-Matched Analysis |
| title_full | Risk Factors for Delirium after Spine Surgery: An Age-Matched Analysis |
| title_fullStr | Risk Factors for Delirium after Spine Surgery: An Age-Matched Analysis |
| title_full_unstemmed | Risk Factors for Delirium after Spine Surgery: An Age-Matched Analysis |
| title_short | Risk Factors for Delirium after Spine Surgery: An Age-Matched Analysis |
| title_sort | risk factors for delirium after spine surgery an age matched analysis |
| topic | Spine Delirium Risk factors Multivariate analysis Hemorrhage |
| url | http://www.asianspinejournal.org/upload/pdf/asj-2018-12-4-703.pdf |
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