Statistical Determination of the Boundaries of Critical Ischemia in Patients with Diabetic Foot Syndrome

Using Cox regression we have analyzed dependence of the probability of amputation and death in patients with critical lower limb ischemia in diabetic foot syndrome on the initial value of the partial pressure of oxygen (ТсРО2). It is found that the conventional boundary of critical ischemia relative...

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Bibliographic Details
Main Author: M.B. Gorobeyko
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2014-09-01
Series:Mìžnarodnij Endokrinologìčnij Žurnal
Subjects:
Online Access:http://iej.zaslavsky.com.ua/article/view/76936
Description
Summary:Using Cox regression we have analyzed dependence of the probability of amputation and death in patients with critical lower limb ischemia in diabetic foot syndrome on the initial value of the partial pressure of oxygen (ТсРО2). It is found that the conventional boundary of critical ischemia relatively risk of high amputations can be considered ТсРО2 14 mmHg. At this pressure the risk of amputation is statistically higher. Risk of low amputations in patients increases with ТсРО2 less than 20 mmHg. The mortality among patients is statistically higher with ТсРО2 less than 20 mmHg. Mortality in groups, in which this parameter is less, is hardly differ. It is advisable to revise the boundary of critical ischemia to ТсРО2 value of 20 mmHg.
ISSN:2224-0721
2307-1427