Lornoxicam use to reduce the pain associated with propofol injection
Aim: To investigate the efficacy of lornoxicam in the prevention of the pain associated with propofol injection. Material and method: Approval for this study was granted by the ethics committee of our hospital. Using a computer randomisation software, 120 patients undergoing elective surgery were as...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2017-01-01
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| Series: | Libyan Journal of Medicine |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/19932820.2017.1313093 |
| _version_ | 1819007034985545728 |
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| author | Nihal Başak Yakup Aksoy Ayhan Kaydu Ömer Fatih Şahin |
| author_facet | Nihal Başak Yakup Aksoy Ayhan Kaydu Ömer Fatih Şahin |
| author_sort | Nihal Başak |
| collection | DOAJ |
| description | Aim: To investigate the efficacy of lornoxicam in the prevention of the pain associated with propofol injection. Material and method: Approval for this study was granted by the ethics committee of our hospital. Using a computer randomisation software, 120 patients undergoing elective surgery were assigned to four equal groups. In Group I (control group), immediately before anaesthesia induction, 10 ml of isotonic 0.9% NaCl solution (placebo) was administered intravenously (IV). In Groups II, III and IV, the same injection contained 2 mg, 4 mg and 8 mg of lornoxicam respectively. A tourniquet was then applied to the forearm for two minutes. Pain evaluation was made using a verbal pain score. Results: Differences in pain severity scores were statistically significant between Groups I and II, Groups I and III, Groups I and IV and between Groups II and III (p < 0.05). However, no significant difference was determined between Groups III and IV (p = 0.401). Conclusion: In all groups administered with lornoxicam, there was a significant reduction in the severity of pain associated with propofol injection, in comparison with the control group. Maximum effect is obtained with a dose of 4 mg. |
| first_indexed | 2024-12-21T00:18:10Z |
| format | Article |
| id | doaj.art-b6f73e30e7f048c9bb50f08d186012f6 |
| institution | Directory Open Access Journal |
| issn | 1993-2820 1819-6357 |
| language | English |
| last_indexed | 2024-12-21T00:18:10Z |
| publishDate | 2017-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Libyan Journal of Medicine |
| spelling | doaj.art-b6f73e30e7f048c9bb50f08d186012f62022-12-21T19:22:09ZengTaylor & Francis GroupLibyan Journal of Medicine1993-28201819-63572017-01-0112110.1080/19932820.2017.13130931313093Lornoxicam use to reduce the pain associated with propofol injectionNihal Başak0Yakup Aksoy1Ayhan Kaydu2Ömer Fatih Şahin3Selahaddin Eyyübi State HospitalBismil State HospitalSelahaddin Eyyübi State HospitalBismil State HospitalAim: To investigate the efficacy of lornoxicam in the prevention of the pain associated with propofol injection. Material and method: Approval for this study was granted by the ethics committee of our hospital. Using a computer randomisation software, 120 patients undergoing elective surgery were assigned to four equal groups. In Group I (control group), immediately before anaesthesia induction, 10 ml of isotonic 0.9% NaCl solution (placebo) was administered intravenously (IV). In Groups II, III and IV, the same injection contained 2 mg, 4 mg and 8 mg of lornoxicam respectively. A tourniquet was then applied to the forearm for two minutes. Pain evaluation was made using a verbal pain score. Results: Differences in pain severity scores were statistically significant between Groups I and II, Groups I and III, Groups I and IV and between Groups II and III (p < 0.05). However, no significant difference was determined between Groups III and IV (p = 0.401). Conclusion: In all groups administered with lornoxicam, there was a significant reduction in the severity of pain associated with propofol injection, in comparison with the control group. Maximum effect is obtained with a dose of 4 mg.http://dx.doi.org/10.1080/19932820.2017.1313093Propofolinjection painlornoxicam |
| spellingShingle | Nihal Başak Yakup Aksoy Ayhan Kaydu Ömer Fatih Şahin Lornoxicam use to reduce the pain associated with propofol injection Libyan Journal of Medicine Propofol injection pain lornoxicam |
| title | Lornoxicam use to reduce the pain associated with propofol injection |
| title_full | Lornoxicam use to reduce the pain associated with propofol injection |
| title_fullStr | Lornoxicam use to reduce the pain associated with propofol injection |
| title_full_unstemmed | Lornoxicam use to reduce the pain associated with propofol injection |
| title_short | Lornoxicam use to reduce the pain associated with propofol injection |
| title_sort | lornoxicam use to reduce the pain associated with propofol injection |
| topic | Propofol injection pain lornoxicam |
| url | http://dx.doi.org/10.1080/19932820.2017.1313093 |
| work_keys_str_mv | AT nihalbasak lornoxicamusetoreducethepainassociatedwithpropofolinjection AT yakupaksoy lornoxicamusetoreducethepainassociatedwithpropofolinjection AT ayhankaydu lornoxicamusetoreducethepainassociatedwithpropofolinjection AT omerfatihsahin lornoxicamusetoreducethepainassociatedwithpropofolinjection |