Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence.

Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence.

Spontaneous testicular teratomas (STTs) derived from primordial germ cells (PGCs) in the mouse embryonic testes predominantly develop in the 129 family inbred strain. Ter (spontaneous mutation) is a single nucleotide polymorphism that generates a premature stop codon of Dead end1 (Dnd1) and increase...

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Bibliographic Details
Main Authors: Atsuki Imai, Yoshihiko Hagiwara, Yuki Niimi, Toshinobu Tokumoto, Yumiko Saga, Atsushi Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232047

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