α11β1 Integrin is Induced in a Subset of Cancer-Associated Fibroblasts in Desmoplastic Tumor Stroma and Mediates In Vitro Cell Migration

α11β1 Integrin is Induced in a Subset of Cancer-Associated Fibroblasts in Desmoplastic Tumor Stroma and Mediates In Vitro Cell Migration

Integrin α11β1 is a collagen receptor that has been reported to be overexpressed in the stroma of non-small cell lung cancer (NSCLC) and of head and neck squamous cell carcinoma (HNSCC). In the current study, we further analyzed integrin α11 expression in 14 tumor types by...

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Bibliographic Details
Main Authors: Cédric Zeltz, Jahedul Alam, Hengshuo Liu, Pugazendhi M. Erusappan, Heinz Hoschuetzky, Anders Molven, Himalaya Parajuli, Edna Cukierman, Daniela-Elena Costea, Ning Lu, Donald Gullberg
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
tumor microenvironment
tumor stroma
extracellular matrix
fibrillar collagen
cancer-associated fibroblasts
integrin alpha11
Online Access:https://www.mdpi.com/2072-6694/11/6/765

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