Computer-assisted tumor grading, validation of PD-L1 scoring, and quantification of CD8-positive immune cell density in urothelial carcinoma, a visual guide for pathologists using QuPath

Computer-assisted tumor grading, validation of PD-L1 scoring, and quantification of CD8-positive immune cell density in urothelial carcinoma, a visual guide for pathologists using QuPath

Abstract Background Advances in digital imaging in pathology and the new capacity to scan high-quality images have change the way to practice and research in surgical pathology. QuPath is an open-source pathology software that offers a reproducible way to analyze quantified variables. We aimed to pr...

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Bibliographic Details
Main Authors: Aline Rodrigues, Cleto Nogueira, Laura Cardoso Marinho, Guilherme Velozo, Juliana Sousa, Paulo Goberlanio Silva, Fabio Tavora
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Surgical and Experimental Pathology
Subjects:
Digital pathology
QuPath
CD8
Tumor infiltrating lymphocytes
Programmed death-ligand 1 immunotherapy
Biomarker
Online Access:https://doi.org/10.1186/s42047-022-00112-y

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