Management of early-onset sepsis in a teaching hospital: A descriptive retrospective study
Objective: To evaluate the management of early-onset sepsis at Saad Abul-Ella Teaching Hospital, Sudan. Methods: A descriptive retrospective hospital-based study was carried out at the Nursery Department of Saad Abul-Ella Teaching Hospital. All medical records of neonates with suspected or confirmed...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Journal of Acute Disease |
| Subjects: | |
| Online Access: | http://www.jadweb.org/article.asp?issn=2221-6189;year=2020;volume=9;issue=2;spage=78;epage=82;aulast=Mohamed |
| _version_ | 1818206176032063488 |
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| author | Sana H Mohamed Rasha R Binni Bashir A Yousef |
| author_facet | Sana H Mohamed Rasha R Binni Bashir A Yousef |
| author_sort | Sana H Mohamed |
| collection | DOAJ |
| description | Objective: To evaluate the management of early-onset sepsis at Saad Abul-Ella Teaching Hospital, Sudan.
Methods: A descriptive retrospective hospital-based study was carried out at the Nursery Department of Saad Abul-Ella Teaching Hospital. All medical records of neonates with suspected or confirmed sepsis during the year 2017 were reviewed to evaluate the management of antibiotics for sepsis using a data collection form.
Results: Out of the 205 cases, 82 neonates (40%) were diagnosed as early-onset sepsis, among which the majority was male (68%). All neonates were given cefotaxime plus vancomycin as empirical therapy which was changed to other antibiotics in 23% of the cases. The common risk factors associated with early-onset sepsis wereprolonged rupture of membrane (41.8%), preterm delivery (26.3%) and low birth weight (15.1%). Blood cultures were performed in 168 cases, and 19% had bacterial growth of Staphylococcus aureus which is the most common isolated pathogen.
Conclusions: Cefotaxime plus vancomycin are the main empirical antibiotic for sepsis, and Staphylococcus aureus is the most common pathogen associated with early-onset sepsis. |
| first_indexed | 2024-12-12T04:08:51Z |
| format | Article |
| id | doaj.art-b70bb4bf94c841b9bf8b915776552346 |
| institution | Directory Open Access Journal |
| issn | 2221-6189 2589-5516 |
| language | English |
| last_indexed | 2024-12-12T04:08:51Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Acute Disease |
| spelling | doaj.art-b70bb4bf94c841b9bf8b9157765523462022-12-22T00:38:41ZengWolters Kluwer Medknow PublicationsJournal of Acute Disease2221-61892589-55162020-01-0192788210.4103/2221-6189.281323Management of early-onset sepsis in a teaching hospital: A descriptive retrospective studySana H MohamedRasha R BinniBashir A YousefObjective: To evaluate the management of early-onset sepsis at Saad Abul-Ella Teaching Hospital, Sudan. Methods: A descriptive retrospective hospital-based study was carried out at the Nursery Department of Saad Abul-Ella Teaching Hospital. All medical records of neonates with suspected or confirmed sepsis during the year 2017 were reviewed to evaluate the management of antibiotics for sepsis using a data collection form. Results: Out of the 205 cases, 82 neonates (40%) were diagnosed as early-onset sepsis, among which the majority was male (68%). All neonates were given cefotaxime plus vancomycin as empirical therapy which was changed to other antibiotics in 23% of the cases. The common risk factors associated with early-onset sepsis wereprolonged rupture of membrane (41.8%), preterm delivery (26.3%) and low birth weight (15.1%). Blood cultures were performed in 168 cases, and 19% had bacterial growth of Staphylococcus aureus which is the most common isolated pathogen. Conclusions: Cefotaxime plus vancomycin are the main empirical antibiotic for sepsis, and Staphylococcus aureus is the most common pathogen associated with early-onset sepsis.http://www.jadweb.org/article.asp?issn=2221-6189;year=2020;volume=9;issue=2;spage=78;epage=82;aulast=Mohamedumbelliferone; type 2 diabetes mellitus; oxidative stress; inflammation; glycation |
| spellingShingle | Sana H Mohamed Rasha R Binni Bashir A Yousef Management of early-onset sepsis in a teaching hospital: A descriptive retrospective study Journal of Acute Disease umbelliferone; type 2 diabetes mellitus; oxidative stress; inflammation; glycation |
| title | Management of early-onset sepsis in a teaching hospital: A descriptive retrospective study |
| title_full | Management of early-onset sepsis in a teaching hospital: A descriptive retrospective study |
| title_fullStr | Management of early-onset sepsis in a teaching hospital: A descriptive retrospective study |
| title_full_unstemmed | Management of early-onset sepsis in a teaching hospital: A descriptive retrospective study |
| title_short | Management of early-onset sepsis in a teaching hospital: A descriptive retrospective study |
| title_sort | management of early onset sepsis in a teaching hospital a descriptive retrospective study |
| topic | umbelliferone; type 2 diabetes mellitus; oxidative stress; inflammation; glycation |
| url | http://www.jadweb.org/article.asp?issn=2221-6189;year=2020;volume=9;issue=2;spage=78;epage=82;aulast=Mohamed |
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