Non-invasive Production of Multi-Compartmental Biodegradable Polymer Microneedles for Controlled Intradermal Drug Release of Labile Molecules

Non-invasive Production of Multi-Compartmental Biodegradable Polymer Microneedles for Controlled Intradermal Drug Release of Labile Molecules

Transdermal drug delivery represents an appealing alternative to conventional drug administration systems. In fact, due to their high patient compliance, the development of dissolvable and biodegradable polymer microneedles has recently attracted great attention. Although stamp-based procedures guar...

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Bibliographic Details
Main Authors: Mario Battisti, Raffaele Vecchione, Costantino Casale, Fabrizio A. Pennacchio, Vincenzo Lettera, Rezvan Jamaledin, Martina Profeta, Concetta Di Natale, Giorgia Imparato, Francesco Urciuolo, Paolo Antonio Netti
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
polymer microneedles
multi-compartmental
enzyme
controlled release
skin model
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00296/full

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