Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study
Background: Recent articles have hypothesized a possible correlation between dental implants dissolution products and peri-implantitis. The null hypothesis tested in this case-control study was that there would be no differences in salivary concentrations of titanium (Ti), vanadium (V), nickel (Ni)...
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| Format: | Article |
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MDPI AG
2020-04-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/5/1264 |
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| author | Piero Papi Andrea Raco Nicola Pranno Bianca Di Murro Pier Carmine Passarelli Antonio D’Addona Giorgio Pompa Maurizio Barbieri |
| author_facet | Piero Papi Andrea Raco Nicola Pranno Bianca Di Murro Pier Carmine Passarelli Antonio D’Addona Giorgio Pompa Maurizio Barbieri |
| author_sort | Piero Papi |
| collection | DOAJ |
| description | Background: Recent articles have hypothesized a possible correlation between dental implants dissolution products and peri-implantitis. The null hypothesis tested in this case-control study was that there would be no differences in salivary concentrations of titanium (Ti), vanadium (V), nickel (Ni) and arsenic (As) ions among patients with dental implants, healthy (Group A) or affected by peri-implantitis (Group B), compared to subjects without implants and/or metallic prosthetic restorations (Group C). Methods: Inductively coupled plasma mass spectrometry was used to analyze saliva samples. One-way repeated-measure analysis of variance (ANOVA) was used to identify statistically significant differences in the salivary level of Ti, V, Ni and As between the three groups. Results: A total of 100 patients were enrolled in the study (42 males and 58 females), distributed in three groups: 50 patients in Group C, 26 patients in Group B and 24 patients Group B. In our study, concentrations of metallic ions were higher in Group A and B, compared to the control group, with the exception of vanadium. However, there were no statistically significant differences (<i>p</i> > 0.05) for metallic ions concentrations between Group A and Group B. Conclusions: Based on our results, there are no differences in titanium or other metals concentrations in saliva of patients with healthy or diseased implants. |
| first_indexed | 2024-03-10T20:12:45Z |
| format | Article |
| id | doaj.art-b70f7056a2674aaeb32a7cd4f8fc43a5 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T20:12:45Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-b70f7056a2674aaeb32a7cd4f8fc43a52023-11-19T22:50:40ZengMDPI AGJournal of Clinical Medicine2077-03832020-04-0195126410.3390/jcm9051264Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control StudyPiero Papi0Andrea Raco1Nicola Pranno2Bianca Di Murro3Pier Carmine Passarelli4Antonio D’Addona5Giorgio Pompa6Maurizio Barbieri7Department of Oral and Maxillo-Facial Sciences, “Sapienza” University of Rome, 00161 Rome, ItalyDepartment of Oral and Maxillo-Facial Sciences, “Sapienza” University of Rome, 00161 Rome, ItalyDepartment of Oral and Maxillo-Facial Sciences, “Sapienza” University of Rome, 00161 Rome, ItalyDepartment of Oral and Maxillo-Facial Sciences, “Sapienza” University of Rome, 00161 Rome, ItalyDivision of Oral Surgery and Implantology, Department of Head and Neck, Oral Surgery, and Implantology Unit, Institute of Clinical Dentistry, Fondazione Policlinico Universitario A. Gemelli IRCCS-Università Cattolica del Sacro Cuore, 00168 Rome, ItalyDivision of Oral Surgery and Implantology, Department of Head and Neck, Oral Surgery, and Implantology Unit, Institute of Clinical Dentistry, Fondazione Policlinico Universitario A. Gemelli IRCCS-Università Cattolica del Sacro Cuore, 00168 Rome, ItalyDepartment of Oral and Maxillo-Facial Sciences, “Sapienza” University of Rome, 00161 Rome, ItalyDepartment of Earth Sciences, “Sapienza” University of Rome, 00161 Rome, ItalyBackground: Recent articles have hypothesized a possible correlation between dental implants dissolution products and peri-implantitis. The null hypothesis tested in this case-control study was that there would be no differences in salivary concentrations of titanium (Ti), vanadium (V), nickel (Ni) and arsenic (As) ions among patients with dental implants, healthy (Group A) or affected by peri-implantitis (Group B), compared to subjects without implants and/or metallic prosthetic restorations (Group C). Methods: Inductively coupled plasma mass spectrometry was used to analyze saliva samples. One-way repeated-measure analysis of variance (ANOVA) was used to identify statistically significant differences in the salivary level of Ti, V, Ni and As between the three groups. Results: A total of 100 patients were enrolled in the study (42 males and 58 females), distributed in three groups: 50 patients in Group C, 26 patients in Group B and 24 patients Group B. In our study, concentrations of metallic ions were higher in Group A and B, compared to the control group, with the exception of vanadium. However, there were no statistically significant differences (<i>p</i> > 0.05) for metallic ions concentrations between Group A and Group B. Conclusions: Based on our results, there are no differences in titanium or other metals concentrations in saliva of patients with healthy or diseased implants.https://www.mdpi.com/2077-0383/9/5/1264dental implantssalivacorrosiontitaniummetallic ions |
| spellingShingle | Piero Papi Andrea Raco Nicola Pranno Bianca Di Murro Pier Carmine Passarelli Antonio D’Addona Giorgio Pompa Maurizio Barbieri Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study Journal of Clinical Medicine dental implants saliva corrosion titanium metallic ions |
| title | Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study |
| title_full | Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study |
| title_fullStr | Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study |
| title_full_unstemmed | Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study |
| title_short | Salivary Levels of Titanium, Nickel, Vanadium, and Arsenic in Patients Treated with Dental Implants: A Case-Control Study |
| title_sort | salivary levels of titanium nickel vanadium and arsenic in patients treated with dental implants a case control study |
| topic | dental implants saliva corrosion titanium metallic ions |
| url | https://www.mdpi.com/2077-0383/9/5/1264 |
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