Blockade of CC Chemokine Receptor Type 3 Diminishes Pain and Enhances Opioid Analgesic Potency in a Model of Neuropathic Pain

Blockade of CC Chemokine Receptor Type 3 Diminishes Pain and Enhances Opioid Analgesic Potency in a Model of Neuropathic Pain

Neuropathic pain is a serious clinical issue, and its treatment remains a challenge in contemporary medicine. Thus, dynamic development in the area of animal and clinical studies has been observed. The mechanisms of neuropathic pain are still not fully understood; therefore, studies investigating th...

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Bibliographic Details
Main Authors: Katarzyna Pawlik, Agata Ciechanowska, Katarzyna Ciapała, Ewelina Rojewska, Wioletta Makuch, Joanna Mika
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
CCR3
neutrophils
morphine
buprenorphine
cytokines
4-aminobenzoic hydrazide
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.781310/full

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