Biosecurity Threat Posed by Botulinum Toxin

The deliberate release of biological agents with terrorist or criminal intent continues to pose concerns in the current geopolitical situation. Therefore, attention is still needed to ensure preparedness against the potential use of pathogens as unconventional weapons. Botulinum neurotoxin (BoNT) is...

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Main Authors: Orlando Cenciarelli, Paul William Riley, Agoritsa Baka
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/11/12/681
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author Orlando Cenciarelli
Paul William Riley
Agoritsa Baka
author_facet Orlando Cenciarelli
Paul William Riley
Agoritsa Baka
author_sort Orlando Cenciarelli
collection DOAJ
description The deliberate release of biological agents with terrorist or criminal intent continues to pose concerns in the current geopolitical situation. Therefore, attention is still needed to ensure preparedness against the potential use of pathogens as unconventional weapons. Botulinum neurotoxin (BoNT) is one such biological threat, characterized by an extremely low lethal dose, high morbidity and mortality when appropriately disseminated, and the capacity to cause panic and social disruption. This paper addresses the risks of a potential release of the botulinum neurotoxin and summarizes the relevant aspects of the threat.
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spelling doaj.art-b710841dc1b447a3b224d184b1eaf5eb2022-12-22T02:07:20ZengMDPI AGToxins2072-66512019-11-01111268110.3390/toxins11120681toxins11120681Biosecurity Threat Posed by Botulinum ToxinOrlando Cenciarelli0Paul William Riley1Agoritsa Baka2European Centre for Disease Prevention and Control (ECDC), Gustav III:s Boulevard 40, 169 73 Solna, SwedenEuropean Centre for Disease Prevention and Control (ECDC), Gustav III:s Boulevard 40, 169 73 Solna, SwedenEuropean Centre for Disease Prevention and Control (ECDC), Gustav III:s Boulevard 40, 169 73 Solna, SwedenThe deliberate release of biological agents with terrorist or criminal intent continues to pose concerns in the current geopolitical situation. Therefore, attention is still needed to ensure preparedness against the potential use of pathogens as unconventional weapons. Botulinum neurotoxin (BoNT) is one such biological threat, characterized by an extremely low lethal dose, high morbidity and mortality when appropriately disseminated, and the capacity to cause panic and social disruption. This paper addresses the risks of a potential release of the botulinum neurotoxin and summarizes the relevant aspects of the threat.https://www.mdpi.com/2072-6651/11/12/681botulinumbotulismbiosecuritybioterrorismbiocrimespoisoning
spellingShingle Orlando Cenciarelli
Paul William Riley
Agoritsa Baka
Biosecurity Threat Posed by Botulinum Toxin
Toxins
botulinum
botulism
biosecurity
bioterrorism
biocrimes
poisoning
title Biosecurity Threat Posed by Botulinum Toxin
title_full Biosecurity Threat Posed by Botulinum Toxin
title_fullStr Biosecurity Threat Posed by Botulinum Toxin
title_full_unstemmed Biosecurity Threat Posed by Botulinum Toxin
title_short Biosecurity Threat Posed by Botulinum Toxin
title_sort biosecurity threat posed by botulinum toxin
topic botulinum
botulism
biosecurity
bioterrorism
biocrimes
poisoning
url https://www.mdpi.com/2072-6651/11/12/681
work_keys_str_mv AT orlandocenciarelli biosecuritythreatposedbybotulinumtoxin
AT paulwilliamriley biosecuritythreatposedbybotulinumtoxin
AT agoritsabaka biosecuritythreatposedbybotulinumtoxin