Biosecurity Threat Posed by Botulinum Toxin
The deliberate release of biological agents with terrorist or criminal intent continues to pose concerns in the current geopolitical situation. Therefore, attention is still needed to ensure preparedness against the potential use of pathogens as unconventional weapons. Botulinum neurotoxin (BoNT) is...
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Format: | Article |
Language: | English |
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MDPI AG
2019-11-01
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Series: | Toxins |
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Online Access: | https://www.mdpi.com/2072-6651/11/12/681 |
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author | Orlando Cenciarelli Paul William Riley Agoritsa Baka |
author_facet | Orlando Cenciarelli Paul William Riley Agoritsa Baka |
author_sort | Orlando Cenciarelli |
collection | DOAJ |
description | The deliberate release of biological agents with terrorist or criminal intent continues to pose concerns in the current geopolitical situation. Therefore, attention is still needed to ensure preparedness against the potential use of pathogens as unconventional weapons. Botulinum neurotoxin (BoNT) is one such biological threat, characterized by an extremely low lethal dose, high morbidity and mortality when appropriately disseminated, and the capacity to cause panic and social disruption. This paper addresses the risks of a potential release of the botulinum neurotoxin and summarizes the relevant aspects of the threat. |
first_indexed | 2024-04-14T06:41:19Z |
format | Article |
id | doaj.art-b710841dc1b447a3b224d184b1eaf5eb |
institution | Directory Open Access Journal |
issn | 2072-6651 |
language | English |
last_indexed | 2024-04-14T06:41:19Z |
publishDate | 2019-11-01 |
publisher | MDPI AG |
record_format | Article |
series | Toxins |
spelling | doaj.art-b710841dc1b447a3b224d184b1eaf5eb2022-12-22T02:07:20ZengMDPI AGToxins2072-66512019-11-01111268110.3390/toxins11120681toxins11120681Biosecurity Threat Posed by Botulinum ToxinOrlando Cenciarelli0Paul William Riley1Agoritsa Baka2European Centre for Disease Prevention and Control (ECDC), Gustav III:s Boulevard 40, 169 73 Solna, SwedenEuropean Centre for Disease Prevention and Control (ECDC), Gustav III:s Boulevard 40, 169 73 Solna, SwedenEuropean Centre for Disease Prevention and Control (ECDC), Gustav III:s Boulevard 40, 169 73 Solna, SwedenThe deliberate release of biological agents with terrorist or criminal intent continues to pose concerns in the current geopolitical situation. Therefore, attention is still needed to ensure preparedness against the potential use of pathogens as unconventional weapons. Botulinum neurotoxin (BoNT) is one such biological threat, characterized by an extremely low lethal dose, high morbidity and mortality when appropriately disseminated, and the capacity to cause panic and social disruption. This paper addresses the risks of a potential release of the botulinum neurotoxin and summarizes the relevant aspects of the threat.https://www.mdpi.com/2072-6651/11/12/681botulinumbotulismbiosecuritybioterrorismbiocrimespoisoning |
spellingShingle | Orlando Cenciarelli Paul William Riley Agoritsa Baka Biosecurity Threat Posed by Botulinum Toxin Toxins botulinum botulism biosecurity bioterrorism biocrimes poisoning |
title | Biosecurity Threat Posed by Botulinum Toxin |
title_full | Biosecurity Threat Posed by Botulinum Toxin |
title_fullStr | Biosecurity Threat Posed by Botulinum Toxin |
title_full_unstemmed | Biosecurity Threat Posed by Botulinum Toxin |
title_short | Biosecurity Threat Posed by Botulinum Toxin |
title_sort | biosecurity threat posed by botulinum toxin |
topic | botulinum botulism biosecurity bioterrorism biocrimes poisoning |
url | https://www.mdpi.com/2072-6651/11/12/681 |
work_keys_str_mv | AT orlandocenciarelli biosecuritythreatposedbybotulinumtoxin AT paulwilliamriley biosecuritythreatposedbybotulinumtoxin AT agoritsabaka biosecuritythreatposedbybotulinumtoxin |