Characteristics of breath sound in infants with risk factors for asthma development
Background: Breath sound parameters have been suggested as biomarkers of the airway narrowing in children. Using a commercially available breath sound analyzer, the characteristics of the airway condition were investigated in infants with the risk factors for asthma development. Methods: A total of...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-01-01
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| Series: | Allergology International |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1323893018300959 |
| _version_ | 1811212768617955328 |
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| author | Hiromi Shioya Hiromi Tadaki Fusae Yamazaki Manabu Miyamoto Shigemi Yoshihara Mayumi Enseki Hideyuki Tabata Kota Hirai Hiroyuki Furuya Masahiko Kato Shuichi Ito Hiroyuki Mochizuki |
| author_facet | Hiromi Shioya Hiromi Tadaki Fusae Yamazaki Manabu Miyamoto Shigemi Yoshihara Mayumi Enseki Hideyuki Tabata Kota Hirai Hiroyuki Furuya Masahiko Kato Shuichi Ito Hiroyuki Mochizuki |
| author_sort | Hiromi Shioya |
| collection | DOAJ |
| description | Background: Breath sound parameters have been suggested as biomarkers of the airway narrowing in children. Using a commercially available breath sound analyzer, the characteristics of the airway condition were investigated in infants with the risk factors for asthma development. Methods: A total of 443 infants (mean age, 9.9 months; range, 3–24 months) were included in the present study. The breath sound parameters of the frequency limiting 99% of the power spectrum (F99), the roll-off from 600 to 1200 Hz (Slope) and spectrum curve indices, the total area under the curve of the dBm data (A3/AT) and the ratio of power and frequency at 50% and 75% of the highest frequency of the power spectrum (RPF75 and RPF50), were evaluated. Using an ATS-DLD based original Japanese questionnaire, we examined the characteristics of airway condition of infants. Results: Finally, 283 infants in good health were included in the present study. The RPF75, RPF50, Slope and F99 in infants with positive results of allergy and atopic dermatitis were significantly increased more than those in the infants with negative result. Conclusions: Our data highlight the characteristics of breath sounds in infants with risk factors for asthma. The breath sound analysis may be useful for assessing the airways of infants for asthma development. Keywords: Asthma, Breath sound analysis, Infant, Risk factors, Sound spectrum |
| first_indexed | 2024-04-12T05:34:48Z |
| format | Article |
| id | doaj.art-b71513de744e4a30a0176fc01adf3829 |
| institution | Directory Open Access Journal |
| issn | 1323-8930 |
| language | English |
| last_indexed | 2024-04-12T05:34:48Z |
| publishDate | 2019-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Allergology International |
| spelling | doaj.art-b71513de744e4a30a0176fc01adf38292022-12-22T03:45:54ZengElsevierAllergology International1323-89302019-01-016819095Characteristics of breath sound in infants with risk factors for asthma developmentHiromi Shioya0Hiromi Tadaki1Fusae Yamazaki2Manabu Miyamoto3Shigemi Yoshihara4Mayumi Enseki5Hideyuki Tabata6Kota Hirai7Hiroyuki Furuya8Masahiko Kato9Shuichi Ito10Hiroyuki Mochizuki11Division of Pediatrics, National Hospital Organization Yokohama Medical Center, Kanagawa, Japan; Corresponding author. Division of Pediatrics, National Hospital Organization Yokohama Medical Center, 3-60-2 Harajyuku, Totsuka, Yokohama, Kanagawa 245-8575, Japan.Division of Pediatrics, Yamato Municipal Hospital, Kanagawa, JapanUchida Iin Y Child Clinic, Kanagawa, JapanDepartment of Pediatrics, Dokkyo Medical University, Tochigi, JapanDepartment of Pediatrics, Dokkyo Medical University, Tochigi, JapanDepartment of Pediatrics, Tokai University School of Medicine, Kanagawa, JapanDepartment of Pediatrics, Tokai University School of Medicine, Kanagawa, JapanDepartment of Pediatrics, Tokai University School of Medicine, Kanagawa, JapanDepartment of Basic Clinical Science and Public Health, Tokai University School of Medicine, Kanagawa, JapanDepartment of Pediatrics, Tokai University School of Medicine, Kanagawa, JapanDepartment of Pediatrics, Yokohama City University School of Medicine, Kanagawa, JapanDepartment of Pediatrics, Tokai University School of Medicine, Kanagawa, JapanBackground: Breath sound parameters have been suggested as biomarkers of the airway narrowing in children. Using a commercially available breath sound analyzer, the characteristics of the airway condition were investigated in infants with the risk factors for asthma development. Methods: A total of 443 infants (mean age, 9.9 months; range, 3–24 months) were included in the present study. The breath sound parameters of the frequency limiting 99% of the power spectrum (F99), the roll-off from 600 to 1200 Hz (Slope) and spectrum curve indices, the total area under the curve of the dBm data (A3/AT) and the ratio of power and frequency at 50% and 75% of the highest frequency of the power spectrum (RPF75 and RPF50), were evaluated. Using an ATS-DLD based original Japanese questionnaire, we examined the characteristics of airway condition of infants. Results: Finally, 283 infants in good health were included in the present study. The RPF75, RPF50, Slope and F99 in infants with positive results of allergy and atopic dermatitis were significantly increased more than those in the infants with negative result. Conclusions: Our data highlight the characteristics of breath sounds in infants with risk factors for asthma. The breath sound analysis may be useful for assessing the airways of infants for asthma development. Keywords: Asthma, Breath sound analysis, Infant, Risk factors, Sound spectrumhttp://www.sciencedirect.com/science/article/pii/S1323893018300959 |
| spellingShingle | Hiromi Shioya Hiromi Tadaki Fusae Yamazaki Manabu Miyamoto Shigemi Yoshihara Mayumi Enseki Hideyuki Tabata Kota Hirai Hiroyuki Furuya Masahiko Kato Shuichi Ito Hiroyuki Mochizuki Characteristics of breath sound in infants with risk factors for asthma development Allergology International |
| title | Characteristics of breath sound in infants with risk factors for asthma development |
| title_full | Characteristics of breath sound in infants with risk factors for asthma development |
| title_fullStr | Characteristics of breath sound in infants with risk factors for asthma development |
| title_full_unstemmed | Characteristics of breath sound in infants with risk factors for asthma development |
| title_short | Characteristics of breath sound in infants with risk factors for asthma development |
| title_sort | characteristics of breath sound in infants with risk factors for asthma development |
| url | http://www.sciencedirect.com/science/article/pii/S1323893018300959 |
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