Secondhand smoke exposure is associated with autism spectrum disorder in US males but not in females: Results from the National Survey on Children's Health
Background: Secondhand smoke (SHS) exposure is linked with neurobehavioral disorders in children. This study evaluated the SHS exposure and autism spectrum disorders (ASD) in children in the United States. Materials and Methods: Parent-reported postnatal SHS exposure and ASD diagnosis were examined...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Environmental Disease |
| Subjects: | |
| Online Access: | http://www.environmentmed.org/article.asp?issn=2468-5690;year=2018;volume=3;issue=1;spage=8;epage=17;aulast=Khalil |
| _version_ | 1818057870086766592 |
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| author | Naila Khalil Bhupinder Kaur Alexandra Lawson James Ebert Ramzi Nahhas |
| author_facet | Naila Khalil Bhupinder Kaur Alexandra Lawson James Ebert Ramzi Nahhas |
| author_sort | Naila Khalil |
| collection | DOAJ |
| description | Background: Secondhand smoke (SHS) exposure is linked with neurobehavioral disorders in children. This study evaluated the SHS exposure and autism spectrum disorders (ASD) in children in the United States.
Materials and Methods: Parent-reported postnatal SHS exposure and ASD diagnosis were examined in children age 2 to 12 years using the 2011–2012 National Survey on Children's Health. The physician diagnosis of current ASD as reported by the parents was used as the outcome. Logistic regression analysis was used to evaluate the association of ASD with SHS after adjusting for risk factors.
Results: Of the 56,710 children, 24% had SHS exposure, 2% had ASD, and the mean age was 7 years. SHS exposure was associated with 47% greater odds of ASD in male children (adjusted odds ratio [OR] = 1.47; 95% confidence interval [CI] =1.05, 2.07; P = 0.025). In contrast, SHS was not significantly associated with ASD in female children (adjusted OR = 0.72; 95% CI = 0.40, 1.29; P = 0.266). Other significant factors associated with ASD diagnosis in male children were age, income, mother's education, and mental health status.
Conclusions: SHS is significantly associated with ASD in male children. Sociodemographic factors, natal and prenatal characteristics are important etiologic influences for ASD. Targeted efforts to change the smoking behavior of parents and caregivers of children could reduce ASD. |
| first_indexed | 2024-12-10T12:51:36Z |
| format | Article |
| id | doaj.art-b7174fa351074be2b17ef01e8b43b02e |
| institution | Directory Open Access Journal |
| issn | 2468-5690 2468-5704 |
| language | English |
| last_indexed | 2024-12-10T12:51:36Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Environmental Disease |
| spelling | doaj.art-b7174fa351074be2b17ef01e8b43b02e2022-12-22T01:48:14ZengWolters Kluwer Medknow PublicationsEnvironmental Disease2468-56902468-57042018-01-013181710.4103/ed.ed_2_18Secondhand smoke exposure is associated with autism spectrum disorder in US males but not in females: Results from the National Survey on Children's HealthNaila KhalilBhupinder KaurAlexandra LawsonJames EbertRamzi NahhasBackground: Secondhand smoke (SHS) exposure is linked with neurobehavioral disorders in children. This study evaluated the SHS exposure and autism spectrum disorders (ASD) in children in the United States. Materials and Methods: Parent-reported postnatal SHS exposure and ASD diagnosis were examined in children age 2 to 12 years using the 2011–2012 National Survey on Children's Health. The physician diagnosis of current ASD as reported by the parents was used as the outcome. Logistic regression analysis was used to evaluate the association of ASD with SHS after adjusting for risk factors. Results: Of the 56,710 children, 24% had SHS exposure, 2% had ASD, and the mean age was 7 years. SHS exposure was associated with 47% greater odds of ASD in male children (adjusted odds ratio [OR] = 1.47; 95% confidence interval [CI] =1.05, 2.07; P = 0.025). In contrast, SHS was not significantly associated with ASD in female children (adjusted OR = 0.72; 95% CI = 0.40, 1.29; P = 0.266). Other significant factors associated with ASD diagnosis in male children were age, income, mother's education, and mental health status. Conclusions: SHS is significantly associated with ASD in male children. Sociodemographic factors, natal and prenatal characteristics are important etiologic influences for ASD. Targeted efforts to change the smoking behavior of parents and caregivers of children could reduce ASD.http://www.environmentmed.org/article.asp?issn=2468-5690;year=2018;volume=3;issue=1;spage=8;epage=17;aulast=KhalilAutismchildrengendersecondhand smoke |
| spellingShingle | Naila Khalil Bhupinder Kaur Alexandra Lawson James Ebert Ramzi Nahhas Secondhand smoke exposure is associated with autism spectrum disorder in US males but not in females: Results from the National Survey on Children's Health Environmental Disease Autism children gender secondhand smoke |
| title | Secondhand smoke exposure is associated with autism spectrum disorder in US males but not in females: Results from the National Survey on Children's Health |
| title_full | Secondhand smoke exposure is associated with autism spectrum disorder in US males but not in females: Results from the National Survey on Children's Health |
| title_fullStr | Secondhand smoke exposure is associated with autism spectrum disorder in US males but not in females: Results from the National Survey on Children's Health |
| title_full_unstemmed | Secondhand smoke exposure is associated with autism spectrum disorder in US males but not in females: Results from the National Survey on Children's Health |
| title_short | Secondhand smoke exposure is associated with autism spectrum disorder in US males but not in females: Results from the National Survey on Children's Health |
| title_sort | secondhand smoke exposure is associated with autism spectrum disorder in us males but not in females results from the national survey on children s health |
| topic | Autism children gender secondhand smoke |
| url | http://www.environmentmed.org/article.asp?issn=2468-5690;year=2018;volume=3;issue=1;spage=8;epage=17;aulast=Khalil |
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