An 18-year experience of tracheoesophageal fistula and esophageal atresia

PurposeTo determine the clinical manifestations and outcomes of patients with tracheoesophageal fistula (TEF) and esophageal atresia (EA) born at a single neonatal intensive care unit.MethodsA retrospective analysis was conducted for 97 patients with confirmed TEF and EA who were admitted to the neo...

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Main Authors: Juhee Seo, Do Yeon Kim, Ai Rhan Kim, Dae Yeon Kim, Seong Chul Kim, In Koo Kim, Ki Soo Kim, Chong Hyun Yoon, Soo Young Pi
Format: Article
Language:English
Published: Korean Pediatric Society 2010-06-01
Series:Korean Journal of Pediatrics
Subjects:
Online Access:http://kjp.or.kr/upload/pdf/kjped-53-705.pdf
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author Juhee Seo
Do Yeon Kim
Ai Rhan Kim
Dae Yeon Kim
Seong Chul Kim
In Koo Kim
Ki Soo Kim
Chong Hyun Yoon
Soo Young Pi
author_facet Juhee Seo
Do Yeon Kim
Ai Rhan Kim
Dae Yeon Kim
Seong Chul Kim
In Koo Kim
Ki Soo Kim
Chong Hyun Yoon
Soo Young Pi
author_sort Juhee Seo
collection DOAJ
description PurposeTo determine the clinical manifestations and outcomes of patients with tracheoesophageal fistula (TEF) and esophageal atresia (EA) born at a single neonatal intensive care unit.MethodsA retrospective analysis was conducted for 97 patients with confirmed TEF and EA who were admitted to the neonatal intensive care unit between 1990 and 2007.ResultsThe rate of prenatal diagnosis was 12%. The average gestational age and birth weight were 37+2 weeks and 2.5±0.7 kg, respectively. Thirty-one infants were born prematurely (32%). Type C was the most common. The mean gap between the proximal and distal esophagus was 2 cm. Esophago-esophagostomy was performed in 72 patients at a mean age of 4 days after birth; gastrostomy or duodenostomy were performed in 8 patients. Forty patients exhibited vertebral, anorectal, cardiac, tracheoesophageal, renal, limb (VACTERL) association with at least 2 combined anomalies, and cardiac anomaly was the most common. The most common post-operative complications were esophageal stricture followed by gastroesophageal reflux. Balloon dilatation was performed for 1.3 times in 26 patients at a mean age of 3 months. The mortality and morbidity rates were 24% and 67%, respectively, and the most common cause of death was sepsis. The weight of approximately 40% patients was below the 10th percentile at 2 years of age.ConclusionMortality and morbidity rates of patients with TEF and EA are high as compared to those of infants with other neonatal surgical diseases. Further efforts must be taken to reduce mortality and morbidity and improve growth retardation.
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spelling doaj.art-b71760e68eb346b5ab006add3c4edd402022-12-22T02:44:41ZengKorean Pediatric SocietyKorean Journal of Pediatrics1738-10612092-72582010-06-0153670571010.3345/kjp.2010.53.6.7052010530606An 18-year experience of tracheoesophageal fistula and esophageal atresiaJuhee Seo0Do Yeon Kim1Ai Rhan Kim2Dae Yeon Kim3Seong Chul Kim4In Koo Kim5Ki Soo Kim6Chong Hyun Yoon7Soo Young Pi8Department of Pediatrics, Ulsan University College of Medicine, Asan Medical Center, Children's Hospital, Seoul, Korea.Department of Pediatrics, Ulsan University College of Medicine, Asan Medical Center, Children's Hospital, Seoul, Korea.Division of Neonatology, Ulsan University College of Medicine, Asan Medical Center, Children's Hospital, Seoul, Korea.Division of Pediatric Surgery, Ulsan University College of Medicine, Asan Medical Center, Children's Hospital, Seoul, Korea.Division of Pediatric Surgery, Ulsan University College of Medicine, Asan Medical Center, Children's Hospital, Seoul, Korea.Division of Pediatric Surgery, Ulsan University College of Medicine, Asan Medical Center, Children's Hospital, Seoul, Korea.Division of Neonatology, Ulsan University College of Medicine, Asan Medical Center, Children's Hospital, Seoul, Korea.Division of Pediatric Radiology, Ulsan University College of Medicine, Asan Medical Center, Children's Hospital, Seoul, Korea.Division of Neonatology, Ulsan University College of Medicine, Asan Medical Center, Children's Hospital, Seoul, Korea.PurposeTo determine the clinical manifestations and outcomes of patients with tracheoesophageal fistula (TEF) and esophageal atresia (EA) born at a single neonatal intensive care unit.MethodsA retrospective analysis was conducted for 97 patients with confirmed TEF and EA who were admitted to the neonatal intensive care unit between 1990 and 2007.ResultsThe rate of prenatal diagnosis was 12%. The average gestational age and birth weight were 37+2 weeks and 2.5±0.7 kg, respectively. Thirty-one infants were born prematurely (32%). Type C was the most common. The mean gap between the proximal and distal esophagus was 2 cm. Esophago-esophagostomy was performed in 72 patients at a mean age of 4 days after birth; gastrostomy or duodenostomy were performed in 8 patients. Forty patients exhibited vertebral, anorectal, cardiac, tracheoesophageal, renal, limb (VACTERL) association with at least 2 combined anomalies, and cardiac anomaly was the most common. The most common post-operative complications were esophageal stricture followed by gastroesophageal reflux. Balloon dilatation was performed for 1.3 times in 26 patients at a mean age of 3 months. The mortality and morbidity rates were 24% and 67%, respectively, and the most common cause of death was sepsis. The weight of approximately 40% patients was below the 10th percentile at 2 years of age.ConclusionMortality and morbidity rates of patients with TEF and EA are high as compared to those of infants with other neonatal surgical diseases. Further efforts must be taken to reduce mortality and morbidity and improve growth retardation.http://kjp.or.kr/upload/pdf/kjped-53-705.pdfTracheoesophageal fistulaEsophageal atresiaVACTERL associationMortalityMorbidityGrowth
spellingShingle Juhee Seo
Do Yeon Kim
Ai Rhan Kim
Dae Yeon Kim
Seong Chul Kim
In Koo Kim
Ki Soo Kim
Chong Hyun Yoon
Soo Young Pi
An 18-year experience of tracheoesophageal fistula and esophageal atresia
Korean Journal of Pediatrics
Tracheoesophageal fistula
Esophageal atresia
VACTERL association
Mortality
Morbidity
Growth
title An 18-year experience of tracheoesophageal fistula and esophageal atresia
title_full An 18-year experience of tracheoesophageal fistula and esophageal atresia
title_fullStr An 18-year experience of tracheoesophageal fistula and esophageal atresia
title_full_unstemmed An 18-year experience of tracheoesophageal fistula and esophageal atresia
title_short An 18-year experience of tracheoesophageal fistula and esophageal atresia
title_sort 18 year experience of tracheoesophageal fistula and esophageal atresia
topic Tracheoesophageal fistula
Esophageal atresia
VACTERL association
Mortality
Morbidity
Growth
url http://kjp.or.kr/upload/pdf/kjped-53-705.pdf
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